procarbazinen.

Brit.

/prəʊˈkɑːbəziːn/, U.S.

/proʊˈkɑrbəˌzin/

Origin: Formed within English, by compounding. Etymons: propyl n., carbamyl n. at carbamide n. Additions, hydrazine n.

Etymology: < pro- (in propyl n.) + carb- (in carbamyl n. at carbamide n. Additions) + -azine (in hydrazine n.).

Pharmacology.

An antineoplastic drug, used esp. in the treatment of lymphomas.Chemical name: N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide; CH₃NHNHCH₂·C₆H₄·CONHCH(CH₃)₂.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tumour

platinum blue1908

nitrogen mustard1943

mustard1945

piperoxan1950

melphalan1960

procarbazine1965

bleomycin1966

1965 Brit. Med. Jrnl. 18 Dec. 1473/1 (heading) Natulan (procarbazine) combined with radiotherapy in management of inoperable malignant melanoma.

1974 R. M. Kirk et al. Surgery iv. 58 Hodgkin's disease (Lymphadenoma)... Generalized disease responds to chemotherapy, usually with a combination of vincristine, mustine, procarbazine and prednisone in pulsed doses.

2005 Drug Week (Nexis) 16 Dec. 181 Temador is indicated for use in adult patients who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.

This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	procarbazine
释义	procarbazinen. Brit. /prəʊˈkɑːbəziːn/, U.S. /proʊˈkɑrbəˌzin/ Origin: Formed within English, by compounding. Etymons: propyl n., carbamyl n. at carbamide n. Additions, hydrazine n. Etymology: < pro- (in propyl n.) + carb- (in carbamyl n. at carbamide n. Additions) + -azine (in hydrazine n.). Pharmacology. An antineoplastic drug, used esp. in the treatment of lymphomas.Chemical name: N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide; CH₃NHNHCH₂·C₆H₄·CONHCH(CH₃)₂. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tumour platinum blue1908 nitrogen mustard1943 mustard1945 piperoxan1950 melphalan1960 procarbazine1965 bleomycin1966 1965 Brit. Med. Jrnl. 18 Dec. 1473/1 (heading) Natulan (procarbazine) combined with radiotherapy in management of inoperable malignant melanoma. 1974 R. M. Kirk et al. Surgery iv. 58 Hodgkin's disease (Lymphadenoma)... Generalized disease responds to chemotherapy, usually with a combination of vincristine, mustine, procarbazine and prednisone in pulsed doses. 2005 Drug Week (Nexis) 16 Dec. 181 Temador is indicated for use in adult patients who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine. This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1965
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