prostacyclinn.

Brit.

/ˌprɒstəˈsʌɪklɪn/, U.S.

/ˌprɑstəˈsaɪkl(ə)n/

Origin: Formed within English, by derivation. Etymons: prostaglandin n., cycle n.¹, -in suffix¹.

Etymology: < prosta- (in prostaglandin n.) + cycl- (in cycle n.¹) + -in suffix¹.

Biochemistry.

Any of a group of prostaglandins, normally produced mainly by endothelial cells, which cause vasodilation and decrease platelet aggregation, and which can be used pharmacologically for these purposes.

ΚΠ

1976 R. A. Johnson et al. Prostaglandins XII. 915 The chemical structure of prostaglandin X..from prostaglandin endoperoxides, is 9-deoxy-6,9α−epoxy−Δ⁵-PGF_1α... The trivial name prostacyclin is proposed for [this].

1987 M. J. Neal Med. Pharmacol. at Glance xxviii. 63/1 Prostacyclin is synthesized in arterial walls.

1992 Lancet 27 June 1554/1 Magnesium inhibits platelet function, perhaps indirectly by release of prostacyclin.

2003 Guardian 19 Aug. ii. 14/3 Ace inhibitors build up defences in the vessel wall against blood clots—these defences are prostacyclins, which lubricate the vessel wall and stop clots sticking to it.

This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	prostacyclin
释义	prostacyclinn. Brit. /ˌprɒstəˈsʌɪklɪn/, U.S. /ˌprɑstəˈsaɪkl(ə)n/ Origin: Formed within English, by derivation. Etymons: prostaglandin n., cycle n.¹, -in suffix¹. Etymology: < prosta- (in prostaglandin n.) + cycl- (in cycle n.¹) + -in suffix¹. Biochemistry. Any of a group of prostaglandins, normally produced mainly by endothelial cells, which cause vasodilation and decrease platelet aggregation, and which can be used pharmacologically for these purposes. ΚΠ 1976 R. A. Johnson et al. Prostaglandins XII. 915 The chemical structure of prostaglandin X..from prostaglandin endoperoxides, is 9-deoxy-6,9α−epoxy−Δ⁵-PGF_1α... The trivial name prostacyclin is proposed for [this]. 1987 M. J. Neal Med. Pharmacol. at Glance xxviii. 63/1 Prostacyclin is synthesized in arterial walls. 1992 Lancet 27 June 1554/1 Magnesium inhibits platelet function, perhaps indirectly by release of prostacyclin. 2003 Guardian 19 Aug. ii. 14/3 Ace inhibitors build up defences in the vessel wall against blood clots—these defences are prostacyclins, which lubricate the vessel wall and stop clots sticking to it. This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1976
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