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单词 prostaglandin
释义

prostaglandinn.

Brit. /ˌprɒstəˈɡlandɪn/, U.S. /ˌprɑstəˈɡlænd(ə)n/
Forms: 1900s– prostaglandin, 1900s– prostoglandin.
Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: prostate n., gland n.2, -in suffix1.
Etymology: < prosta- (in prostate n.) + gland n.2 + -in suffix1, after German Prostaglandin (U. S. von Euler 1935, in Klin. Wochenschr. 17 Aug. 1183/1).So called because when first isolated from seminal fluid, prostaglandin was believed to be part of the prostatic secretions. With the form prostoglandin compare -o- connective.
Biochemistry.
Any of a large group of unsaturated, oxygenated fatty acids which have a wide variety of physiological effects, esp. in the control of smooth muscle activity (in the uterus, blood vessels, bronchia, etc.) and in inflammatory responses.The prostaglandins have molecular structures based on that of prostanoic acid.
ΚΠ
1936 U. S. von Euler in Jrnl. Physiol. 88 233 In secretion and extracts from the prostate and seminal vesicles of man and the vesicular gland of the sheep a pharmacodynamically highly active substance, prostaglandin, has been demonstrated.
1965 Sun 2 Nov. 11/1 It is thought that prostaglandins may work by acting on the woman's reproductive muscles, so helping the process of conception.
1985 M. F. Myles Textbk. Midwives (ed. 10) x. 166 Prostaglandin E2 by the extraovular route may be used to induce abortion.
1993 Independent on Sunday 4 Apr. 8/2 The injections of prostaglandin or a drug called papaverine relax smooth muscle tissue in the penis to produce an erection.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1936
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