prurigon.

a1646 J. Gregory Posthuma (1649) 102 A Fever hee had, but not of anie acute kinde: an unsufferable Prurigo over all his bodie.

1686 T. Pierce Law & Equity Gospel 613 (heading) An Amulet or Præservative Against the Prurigo of Ambition.

1733 S.-Carolina Gaz. 7 July 3/1 And thirdly, for that, if confined to proper external Bounds, [the Corn-kob] may be delightfully employed, by any one affected with a Prurigo of any Kind in those lower Regions.

1779 A. Baxter Evidence of Reason 251 The uneasiness indeed of a prurigo is different from that of a wound or a bruise.

1829 J. Togno & E. Durand tr. H. Milne-Edwards & P. Vavasseur Man. Materia Medica vi. 164 The skin..becomes the seat of a very lively pricking, of prurigo, and of an abundant perspiration.

1798 R. Willan Descr. & Treatm. Cutaneous Dis. i. 71 There are some cases in which it [sc. the symptom of itching] occurs as the leading circumstance, and is at the same time, accompanied with an eruption of papulæ, the colour of which scarcely exceeds that of the adjoining cuticle, and with other appearances sufficiently particular to constitute a distinct and independent genus of disease. To this therefore I shall apply the denomination of Prurigo.

1896 N. Walker tr. P. G. Unna Histopathol. Dis. Skin ii. 132 With Hebra I regard as ‘Prurigo’ only those severely itching dermatoses which present primary nodules of peculiar character, while the name ‘pruritus’ indicates every form of itching neurosis of the skin, which is not accompanied by a primary eruption.

1910 J. N. Hyde Pract. Treat. Dis. Skin (ed. 8) 170 Prurigo is a chronic, exudative, cutaneous affection.

1968 H. O. Mackey & J. P. Mackey Handbk. Dis. Skin (ed. 9) xv. 130 Two varieties of prurigo are described (1) prurigo mitis (Willan), a comparatively mild type, and (2) prurigo ferox, or prurigo agria (Hebra), a very severe, though rare type.

1996 Jrnl. Investigative Dermatol. 106 362 Human leukocyte antigen (HLA) associations have been reported in Amerindian patients with actinic prurigo.