单词 | purine |
释义 | purinen. Chemistry. A crystalline, basic, heterocyclic compound whose molecule is the basis of many naturally occurring substances such as caffeine and xanthine; any substituted derivative of this compound, esp. = purine base n. at Compounds 2.Purine has a planar bicyclic molecule consisting of fused imidazole and pyrimidine rings. Formula: C5H4N4O3. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > cyclic compounds > bicyclic compounds purine1898 halowax1922 spirolactone1958 1885 Jrnl. Amer. Chem. Soc. 7 29 The author regards these compounds as derivatives of the hitherto unknown hydrogen compound CH3C5N4H3, which he calls methylpurine.] 1898 Chem. News 16 Dec. 304/1 (heading) Molecular transformation in the group of purines. 1899 Jrnl. Chem. Soc. 76 i. 175 Purine,..is a readily soluble, well crystallised substance, which forms salts both with acids and with bases, and as regards its character in general falls naturally in the series uric acid, xanthine, hypoxanthine, purine. 1934 C. C. Steele Introd. Plant Biochem. v. xvi. 171 Uric acid, and some other purines, e.g. xanthine and caffeine, are readily detected by the murexide test. 1973 R. G. Krueger et al. Introd. Microbiol. x. 307/2 Pairings between purines would distort the helix because of the large size of the molecules. 1994 Independent on Sunday 13 Feb. 23/7 The breakdown of purines creates uric acid, the immediate cause of gout. 2000 J. A. Joule & K. Mills Heterocyclic Chem. (ed. 4) xxiv. 468 The 3-oxide of purine itself has been obtained via oxidation of 6-cyanopurine..then hydrolysis and decarboxylation. Compounds C1. General attributive. ΚΠ 1900 Lancet 29 Dec. 1893/2 The position of the purin or xanthin bodies in general metabolism. 1921 Spectator 21 May 658/1 Purin bodies, precursors of uric acid, and purin-free diets have likewise had their day, although as inculcating abstemiousness the latter played a useful part. 1970 Nature 25 July 379/2 Naturally occurring cytokinins known so far have a purine nucleus as the essential moiety. 1997 G. S. Helfman et al. Diversity of Fishes x. 136/2 Smolts... The silvering results from an increase in the density of purine crystals, mostly guanine but also hypoxanthine, which are deposited beneath scales and deep within the dermis. 2003 Proc. National Acad. Sci. U.S.A. 10 15396 The hydrolysis of purine nucleotides is weakly concerted. C2. purine base n. a base with a structure related to purine; spec. either of the nucleotide-forming bases adenine and guanine. ΚΠ 1903 Jrnl. Chem. Soc. 84 ii. 679 Various fungi..decompose nucleic acid with the liberation of phosphoric acid and purine bases. 1933 S. W. Cole Pract. Physiol. Chem. (ed. 9) iv. 104 (table) Thymus nucleic acid. Phosphoric acid (4 mols.) 2-desoxy-aldo-pentose (4 mols.)..Guanine..Adenine..Purine bases. Cytosine..Thymine..Pyrimidine bases. 1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) vi. 121 Uric acid is derived from the catabolism of nucleo-protein, which is hydrolysed first to nucleic acid and then to the purin bases; uric acid is trioxy-purin. 1990 Nucleic Acids Res. 18 4081/1 In all sequences studied here containing a wobble mispair, the purine base at the mispair site shifts into the minor groove. This entry has been updated (OED Third Edition, September 2007; most recently modified version published online March 2022). < n.1898 |
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