单词 | pyridostigmine |
释义 | pyridostigminen. Pharmacology. More fully pyridostigmine bromide. A cholinesterase inhibitor structurally related to neostigmine but having a longer duration of action and fewer side effects, used in the treatment of myasthenia gravis, and also given to provide pre-exposure protection against nerve gases.Chemical name: 3-dimethylcarbamoyloxy-1-methylpyridinium bromide, C9H13BrN2O2. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for myasthenia Prostigmine1931 neostigmine1943 pyridostigmine1953 1953 Jrnl. Amer. Med. Assoc. 12 Sept. 175/1 Since 1948, a pyridine homologue of neostigmine (Pyridostigmine) was given a therapeutic trial in 23 patients with myasthenia gravis associated with pseudoparalysis. 1967 Anesthesiology 28 528 (title) Pyridostigmin (mestinon) as an antagonist of d-tubocurarine. 1993 Brit. Jrnl. Surg. 80 223/2 After operation frank myasthenia developed, initially requiring ventilation but responding well to pyridostigmine. 2000 L. Crane Ninth Day of Creation 423 Tulloch had urged funding for..an anti-nerve agent drug called pyridostigmine bromide, anticipating by six years the eventual conflict with Iraq. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < n.1953 |
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