quinazolinen.

Brit.

/kwᵻˈnazəliːn/,

/kwᵻˈnazəlɪn/, U.S.

/kwəˈnæzəl(ə)n/

Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: quinoline n., azo- comb. form.

Etymology: < quinoline n., with inserted az- (see azo- comb. form), after German Chinazolin (A. Weddige 1887, in Jrnl. f. prakt. Chem. 36 142).

Chemistry.

A yellow, basic, crystalline solid, which has a bicyclic structure formed from fused benzene and pyrimidine rings; any substituted derivative of this.Formula: C₈H₆N₂.

ΘΚΠ

the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > other heterocyclic compounds

alloxan1839

piperidine1854

valerin1866

acridine1870

piperidia1871

kairoline1883

quinoxaline1884

pyrimidine1885

pyrazolone1887

quinazoline1887

pyrazine1888

acridone1892

phthalazine1893

pyridazine1894

nitron1906

pyrrolizidine1939

1887 Jrnl. Chem. Soc. 52 ii. 1044 Anhydroacetyl~orthamidobenzamide is regarded as a derivative of a hypothetical base, quinazoline,..isomeric with cinnoline and quinoxaline.

1903 Jrnl. Chem. Soc. 84 i. 446 By oxidising this base with potassium ferricyanide, quinazoline..was at last successfully prepared; it..crystallises from light petroleum in glistening flakes resembling naphthalene, has a bitter, burning taste, and..is odourless at the ordinary temperature.

1926 H. G. Rule tr. J. Schmidt Text-bk. Org. Chem. 700 Quinazolines..are strong bases, which are readily reduced to their dihydro-compounds.

1950 Thorpe's Dict. Appl. Chem. (ed. 4) X. 346/2 A variety of substituted quinazolines have been prepared recently as part of the search for effective antimalarials.

1993 European Urol. 24 319 Doxazosin, a once-daily quinazoline derivative.., was evaluated in the treatment of BPH [= benign prostatic hyperplasia].

This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).

单词	quinazoline
释义	quinazolinen. Brit. /kwᵻˈnazəliːn/, /kwᵻˈnazəlɪn/, U.S. /kwəˈnæzəl(ə)n/ Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: quinoline n., azo- comb. form. Etymology: < quinoline n., with inserted az- (see azo- comb. form), after German Chinazolin (A. Weddige 1887, in Jrnl. f. prakt. Chem. 36 142). Chemistry. A yellow, basic, crystalline solid, which has a bicyclic structure formed from fused benzene and pyrimidine rings; any substituted derivative of this.Formula: C₈H₆N₂. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > heterocyclic compounds > other heterocyclic compounds alloxan1839 piperidine1854 valerin1866 acridine1870 piperidia1871 kairoline1883 quinoxaline1884 pyrimidine1885 pyrazolone1887 quinazoline1887 pyrazine1888 acridone1892 phthalazine1893 pyridazine1894 nitron1906 pyrrolizidine1939 1887 Jrnl. Chem. Soc. 52 ii. 1044 Anhydroacetyl~orthamidobenzamide is regarded as a derivative of a hypothetical base, quinazoline,..isomeric with cinnoline and quinoxaline. 1903 Jrnl. Chem. Soc. 84 i. 446 By oxidising this base with potassium ferricyanide, quinazoline..was at last successfully prepared; it..crystallises from light petroleum in glistening flakes resembling naphthalene, has a bitter, burning taste, and..is odourless at the ordinary temperature. 1926 H. G. Rule tr. J. Schmidt Text-bk. Org. Chem. 700 Quinazolines..are strong bases, which are readily reduced to their dihydro-compounds. 1950 Thorpe's Dict. Appl. Chem. (ed. 4) X. 346/2 A variety of substituted quinazolines have been prepared recently as part of the search for effective antimalarials. 1993 European Urol. 24 319 Doxazosin, a once-daily quinazoline derivative.., was evaluated in the treatment of BPH [= benign prostatic hyperplasia]. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < n.1887
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