quinicadj.

Brit.

/ˈkwɪnɪk/, U.S.

/ˈkwɪnɪk/

Forms: 1800s– chinic, 1800s– kinic Brit.

/ˈkɪnɪk/, U.S.

/ˈkɪnɪk/, 1800s– quinic.

Origin: Formed within English, by derivation; partly modelled on a French lexical item. Etymons: quina n., -ic suffix.

Etymology: < quina n. + -ic suffix, partly after French kinique (in acide kinique: Vauquelin 1806, in Annales de chimie 59 167; also quinique (1827 or earlier)), itself apparently after German Chinasäure (Hofmann 1790, in Chemische Ann. 2 316).

1. Chemistry.

a. quinic acid n. a crystalline carboxylic acid found in cinchona bark and in various fruits and leaves, and used in the synthesis of pharmaceuticals.Quinic acid has a cyclic structure. Formula: C₆H₇(OH)₄COOH.

ΚΠ

1813 H. Davy Elements Agric. Chem. iii. 95 The kinic acid in a salt afforded by Peruvian bark.

1853 D. Breed tr. C. Löwig Princ. Org. & Physiol. Chem. 194 Chinon is obtained when chinic acid or a chinic acid salt, is warmed with 4 parts manganese, 1 part sulphuric acid, and 1 part water.

1880 C. R. Markham Peruvian Bark 31 In 1803 another chemist found a crystalline substance in the bark which..was nothing more than the combination of lime with an acid which was named quinic acid.

1934 C. C. Steele Introd. Plant Biochem. vi. xvii. 180 Quinone is..obtained by the oxidation of quinic acid from cinchona bark.

1993 Sci. Amer. Nov. 79/1 A biotechnology firm..is considering setting up a pilot plant that will use glucose to make quinic acid, a starting material for the feedstock hydroquinone.

†b. quinic ether n. an ester of quinic acid; spec. ethyl quinate. Obsolete.

ΚΠ

1859 Chem. News 1 11/2 Quinic ether is prepared by the reaction of one equivalent of iodide of ethyl upon one equivalent of quinate of silver.

1860 New Sydenham Soc. Year-bk. (1861) 413 Quinic ether inhalations in ague.

†2. Medicine. Occurring as an adverse reaction to treatment with or exposure to quinine. Obsolete. rare. quinic fever n. fever and rash occurring as an occupational hypersensitivity reaction to quinine.

ΚΠ

1890 G. M. Gould New Med. Dict. 373/2 Quinic fever, febrile symptoms with an eruption; occurs among the workmen making quinine.

1894 Lancet 1 Dec. 1314/1 This visual trouble had come on one morning after the ingestion (on the previous evening) of four teaspoonfuls of sulphate of quinine... As a rule, this quinic amblyopia disappears rapidly.

This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).

单词	quinic
释义	quinicadj. Brit. /ˈkwɪnɪk/, U.S. /ˈkwɪnɪk/ Forms: 1800s– chinic, 1800s– kinic Brit. /ˈkɪnɪk/, U.S. /ˈkɪnɪk/, 1800s– quinic. Origin: Formed within English, by derivation; partly modelled on a French lexical item. Etymons: quina n., -ic suffix. Etymology: < quina n. + -ic suffix, partly after French kinique (in acide kinique: Vauquelin 1806, in Annales de chimie 59 167; also quinique (1827 or earlier)), itself apparently after German Chinasäure (Hofmann 1790, in Chemische Ann. 2 316). 1. Chemistry. a. quinic acid n. a crystalline carboxylic acid found in cinchona bark and in various fruits and leaves, and used in the synthesis of pharmaceuticals.Quinic acid has a cyclic structure. Formula: C₆H₇(OH)₄COOH. ΚΠ 1813 H. Davy Elements Agric. Chem. iii. 95 The kinic acid in a salt afforded by Peruvian bark. 1853 D. Breed tr. C. Löwig Princ. Org. & Physiol. Chem. 194 Chinon is obtained when chinic acid or a chinic acid salt, is warmed with 4 parts manganese, 1 part sulphuric acid, and 1 part water. 1880 C. R. Markham Peruvian Bark 31 In 1803 another chemist found a crystalline substance in the bark which..was nothing more than the combination of lime with an acid which was named quinic acid. 1934 C. C. Steele Introd. Plant Biochem. vi. xvii. 180 Quinone is..obtained by the oxidation of quinic acid from cinchona bark. 1993 Sci. Amer. Nov. 79/1 A biotechnology firm..is considering setting up a pilot plant that will use glucose to make quinic acid, a starting material for the feedstock hydroquinone. †b. quinic ether n. an ester of quinic acid; spec. ethyl quinate. Obsolete. ΚΠ 1859 Chem. News 1 11/2 Quinic ether is prepared by the reaction of one equivalent of iodide of ethyl upon one equivalent of quinate of silver. 1860 New Sydenham Soc. Year-bk. (1861) 413 Quinic ether inhalations in ague. †2. Medicine. Occurring as an adverse reaction to treatment with or exposure to quinine. Obsolete. rare. quinic fever n. fever and rash occurring as an occupational hypersensitivity reaction to quinine. ΚΠ 1890 G. M. Gould New Med. Dict. 373/2 Quinic fever, febrile symptoms with an eruption; occurs among the workmen making quinine. 1894 Lancet 1 Dec. 1314/1 This visual trouble had come on one morning after the ingestion (on the previous evening) of four teaspoonfuls of sulphate of quinine... As a rule, this quinic amblyopia disappears rapidly. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < adj.1813
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