reactogenicadj.

Brit.

/rɪˌaktəˈdʒɛnɪk/, U.S.

/riˌæktəˈdʒɛnɪk/

Origin: Formed within English, by compounding. Etymons: reaction n., -o- connective, -genic comb. form.

Etymology: < react- (in reaction n.) + -o- connective + -genic comb. form. Compare earlier immunogenic adj.

Medicine and Immunology.

Of or relating to the production of adverse reactions (in immunization); producing an adverse reaction.

ΚΠ

1959 Bull. World Health Organization 20 1053 (title) Results of a study of the reactogenic and immunogenic properties of live anti-poliomyelitis vaccine.

1980 Lancet 19 Jan. 148/2 It may be that the routine batch of AV [= adsorbed vaccine] that we used for this trial was abnormally reactogenic.

2006 Jrnl. Infectious Dis. 194 444 Vaccinia virus is reactogenic in a significant number of vaccinees, with the most common adverse events being fever, lymphadenopathy, and rash.

Derivatives

reactogeˈnicity n. reactogenic property.

ΚΠ

1965 Bull. World Health Organization 32 637 (title) Safety tests and reactogenicity studies on a live dysentery vaccine intended for use in field trials.

2000 Philos. Trans. (Royal Soc.) B. 355 706/1 Perhaps the biggest challenge facing new live vaccines is obtaining the balance between optimal immunogenicity with an absence of reactogenicity in the vaccine.

This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022).

单词	reactogenic
释义	reactogenicadj. Brit. /rɪˌaktəˈdʒɛnɪk/, U.S. /riˌæktəˈdʒɛnɪk/ Origin: Formed within English, by compounding. Etymons: reaction n., -o- connective, -genic comb. form. Etymology: < react- (in reaction n.) + -o- connective + -genic comb. form. Compare earlier immunogenic adj. Medicine and Immunology. Of or relating to the production of adverse reactions (in immunization); producing an adverse reaction. ΚΠ 1959 Bull. World Health Organization 20 1053 (title) Results of a study of the reactogenic and immunogenic properties of live anti-poliomyelitis vaccine. 1980 Lancet 19 Jan. 148/2 It may be that the routine batch of AV [= adsorbed vaccine] that we used for this trial was abnormally reactogenic. 2006 Jrnl. Infectious Dis. 194 444 Vaccinia virus is reactogenic in a significant number of vaccinees, with the most common adverse events being fever, lymphadenopathy, and rash. Derivatives reactogeˈnicity n. reactogenic property. ΚΠ 1965 Bull. World Health Organization 32 637 (title) Safety tests and reactogenicity studies on a live dysentery vaccine intended for use in field trials. 2000 Philos. Trans. (Royal Soc.) B. 355 706/1 Perhaps the biggest challenge facing new live vaccines is obtaining the balance between optimal immunogenicity with an absence of reactogenicity in the vaccine. This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022). < adj.1959
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