remdesivirn.

Brit.

/rɛmˈdɛsᵻvɪə/,

/rɛmˈdɛzᵻvɪə/, U.S.

/rɛmˈdɛsəvɪ(ə)r/,

/rɛmˈdɛzəvɪ(ə)r/

Origin: Formed within English, by compounding. Etymons: rem- , adenosine n., virus n.

Etymology: < rem-, probably an arbitrary element + -desi-, denoting an adenosine analogue (probably < -de- and -si- in adenosine n.) + -vir, combining form denoting an antiviral compound ( < virus n.).

Pharmacology.

An antiviral prodrug used to treat RNA virus infections, including Ebola fever and coronavirus diseases such as SARS and MERS.Chemical formula: C₂₇H₃₅N₆O₈P (see quot. 2017).Remdesivir is metabolized to form a nucleoside analogue which blocks the action of viral RNA polymerase and prevents the virus from replicating.

ΚΠ

2017 WHO Drug Info. 31 549 Remdesivir. 2-ethylbutyl N-{(S)-[2-C-(4-aminopyrrolo[2, 1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitril-6-O-yl]phenoxyphosphoryl}-L-alaninate.

2018 mBio 9 (online journal, accessed 13 Nov. 2020) The nucleoside analogue GS-5734 (remdesivir) potently inhibits human and zoonotic CoVs in vitro and in a severe acute respiratory syndrome coronavirus (SARS-CoV) mouse model.

2020 Wall St. Jrnl. 8 Aug. a7/1 Gilead Sciences Inc. is expanding its manufacturing network to ramp up production of Covid-19 treatment remdesivir, and says it will be able to meet global demand in real time starting in October.

This is a new entry (OED Third Edition, June 2021; most recently modified version published online March 2022).

单词	remdesivir
释义	remdesivirn. Brit. /rɛmˈdɛsᵻvɪə/, /rɛmˈdɛzᵻvɪə/, U.S. /rɛmˈdɛsəvɪ(ə)r/, /rɛmˈdɛzəvɪ(ə)r/ Origin: Formed within English, by compounding. Etymons: rem- , adenosine n., virus n. Etymology: < rem-, probably an arbitrary element + -desi-, denoting an adenosine analogue (probably < -de- and -si- in adenosine n.) + -vir, combining form denoting an antiviral compound ( < virus n.). Pharmacology. An antiviral prodrug used to treat RNA virus infections, including Ebola fever and coronavirus diseases such as SARS and MERS.Chemical formula: C₂₇H₃₅N₆O₈P (see quot. 2017).Remdesivir is metabolized to form a nucleoside analogue which blocks the action of viral RNA polymerase and prevents the virus from replicating. ΚΠ 2017 WHO Drug Info. 31 549 Remdesivir. 2-ethylbutyl N-{(S)-[2-C-(4-aminopyrrolo[2, 1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitril-6-O-yl]phenoxyphosphoryl}-L-alaninate. 2018 mBio 9 (online journal, accessed 13 Nov. 2020) The nucleoside analogue GS-5734 (remdesivir) potently inhibits human and zoonotic CoVs in vitro and in a severe acute respiratory syndrome coronavirus (SARS-CoV) mouse model. 2020 Wall St. Jrnl. 8 Aug. a7/1 Gilead Sciences Inc. is expanding its manufacturing network to ramp up production of Covid-19 treatment remdesivir, and says it will be able to meet global demand in real time starting in October. This is a new entry (OED Third Edition, June 2021; most recently modified version published online March 2022). < n.2017
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