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单词 replicase
释义

replicasen.

Brit. /ˈrɛplᵻkeɪz/, U.S. /ˈrɛpləˌkeɪz/, /ˈrɛpləˌkeɪs/
Origin: Formed within English, by derivation. Etymons: replicate v., replication n., -ase suffix.
Etymology: < replic- (in replicate v., replication n.) + -ase suffix.
Biochemistry.
An enzyme which brings about the replication of a nucleic acid; esp. a polymerase which effects the synthesis of a complementary RNA molecule using an RNA template.
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the world > life > biology > biological processes > genetic activity > genetic components > [noun] > nucleic acid > enzymes
galactase1898
cellulase1901
nuclease1902
xanthine oxidase1905
exoenzyme1908
glucosidase1909
galactase1910
nucleosidase1911
nucleotidase1911
adenosine deaminase1913
cellobiase1919
hydratase1922
activase1928
hexokinase1930
histaminase1930
kallikrein1930
Michaelis constant1930
cholinesterase1932
phosphodiesterase1932
chymotrypsin1933
glycosidase1933
rhodanese1933
acetylcholinesterase1937
prolidase1937
diaphorase1938
aconitase1939
hyaluronidase1940
transaminase1940
hydrase1943
isomerase1943
lactoperoxidase1943
streptokinase1944
pectinesterase1945
pectinmethylesterase1945
phosphokinase1946
alliinase1947
CoA1947
phosphotransferase1948
polymerase1948
transferase1948
elastase1949
amyloglucosidase1950
transacetylase1950
transhydrogenase1952
hydroxylase1953
kinase1953
transketolase1953
synthase1954
hexosaminidase1955
translocase1957
angiotensinase1958
angiotensin converting enzyme1960
photoenzyme1960
acetyltransferase1961
adenyl cyclase1961
adenylate cyclase1962
replicase1962
ADA1963
transcriptase1963
adenylyl cyclase1964
recombinase1964
laminarinase1966
nickase1967
acrosin1970
reverse transcriptase1970
cellobiohydrolase1972
cyclooxygenase1974
laminaranase1974
primase1977
helicase1978
monodeiodinase1978
transposase1979
maturase1980
1962 S. S. Cohen in Jrnl. Pediatrics 60 594/1 The enzyme, known as a DNA polymerase, acts as a ‘replicase’.
1963 S. Spiegelman & M. Hayashi in Cold Spring Harbor Symp. Quantitative Biol. 28 162/1 The RNA-dependent-RNA-polymerase which replicates RNA will be called a replicase.
1983 Proc. National Acad. Sci. U.S.A. 80 969/1 These studies using transcriptases have now been extended to the use of replicases, enzymes that normally duplicate polynucleotides, making DNA on a DNA template or RNA on a RNA template.
1990 EMBO Jrnl. 9 2665/2 Replication of the viral genome in plus strand (messenger-sense) RNA viruses occurs initially via synthesis of complementary minus strand RNA by the viral replicase.
2005 C. de Duve Singularities ix. 116 The viral RNA, known as a plus strand, acts as messenger. It is translated by the cell to give the replicase, which then starts to function.
This entry has been updated (OED Third Edition, December 2009; most recently modified version published online March 2022).
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n.1962
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