单词 | reverse genetics |
释义 | > as lemmasreverse genetics reverse genetics n. an approach used in genetic analysis in which a known sequence of DNA is mutated with a view to examining the effects of such a mutation on gene function and resulting phenotype; frequently contrasted with classical genetics; cf. positional cloning n. at positional adj. Compounds. ΚΠ 1981 D. Shortle et al. in Ann. Rev. Genetics 15 266 It is now possible to construct mutations at predetermined sites in a cloned DNA molecule, precisely define the chemical nature of the mutational change, and then test the functional effect of the mutation in vitro and/or in vivo. This approach to mutational analysis has been termed ‘reverse genetics’. 1995 D. J. Weatherall Sci. & Quiet Art (1996) viii. 256 This unlikely activity, which was originally called reverse genetics but which has since been rechristened positional cloning, represents one of the most important developments in molecular medicine. 2004 San Francisco Chron. (Nexis) 29 Jan. a1 Reverse genetics allows researchers to assemble designer flu viruses, using biotechnology tools to remove viral traits that make a particular strain lethal. < as lemmas |
随便看 |
英语词典包含1132095条英英释义在线翻译词条,基本涵盖了全部常用单词的英英翻译及用法,是英语学习的有利工具。