bioavailabilityn.
/ˌbʌɪəʊəˌveɪləˈbɪlᵻti/, U.S. /ˌbaɪoʊəˌveɪləˈbɪlᵻdi/ Physiology and Pharmacology.
The degree to which a drug or other substance is absorbed or reaches a target site in the body; esp. the proportion of a dose of a drug taken orally which reaches the bloodstream.
ΘΚΠ
the world > health and disease > healing > medicines or physic > [noun] > portion of drug which reaches site
bioavailability1961
the world > life > the body > vascular system > circulation > [noun] > proportion of substance entering
bioavailability1961
1961 Pfizer European Agric. Res. Conf. Proc. 51 The relationship between particle size of vitamin A and excretion is further correlated with bio-availability based on blood and liver levels of vitamin A.
1971 Compton Yearbk. 224/2 The FDA began to insist that any claims of bioavailability equivalency made by the makers of generic drugs be true.
1983 D. J. Weatherall et al. Oxf. Textbk. Med. I. vii. 5/2 By definition, the bioavailability of a drug after intravenous administration is 100 per cent.
1985 Brit. Med. Jrnl. 9 Nov. 1332/2 The bioavailability of iron in domestic water supplies is not known.
2000 W. Cabri & R. Di Fabio From Bench to Market v. 100 In healthy humans the oral bioavailability of ritipenem acoxil is 37–42%.
This entry has been updated (OED Third Edition, November 2010; most recently modified version published online December 2021).
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n.1961