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单词 bioequivalent
释义

bioequivalentadj.

Brit. /ˌbʌɪəʊᵻˈkwɪvələnt/, /ˌbʌɪəʊᵻˈkwɪvəln̩t/, /ˌbʌɪəʊᵻˈkwɪvl̩(ə)nt/, U.S. /ˌbaɪoʊəˈkwɪv(ə)lənt/, /ˌbaɪoʊiˈkwɪv(ə)lənt/; see also equivalent adj. and n.
Origin: Formed within English, by compounding. Etymons: bio- comb. form, equivalent adj.
Etymology: < bio- comb. form + equivalent adj., after bioequivalence n., bioequivalency n.
Pharmacology.
Of different preparations or formulations of a drug or other pharmaceutical product: having equivalent bioavailability and pharmacokinetic properties.
ΚΠ
1973 J. D. Cooper Efficacy of Self-medication vi. 179 If there are a number of drugs which are safe, bioequivalent, and efficacious, they are compounded in a range of colors.
1985 Science 20 Sept. 1247/1 Hoffman–La Roche..tried to block FDA approval of generic diazepams, asserting that they were not bioequivalent to Valium.
2008 Wall St. Jrnl. 22 Apr. d1/2 Generics can produce blood levels as much as 20% below..that of the original drug and still be considered ‘bioequivalent’, according to Food and Drug Administration guidelines.
This is a new entry (OED Third Edition, November 2010; most recently modified version published online December 2021).
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adj.1973
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