biolisticadj.
/ˌbʌɪəˈlɪstɪk/, U.S. /ˌbaɪəˈlɪstɪk/ Genetics.
Designating a procedure for introducing DNA into plant or animal cells by injecting into them microscopic particles of a heavy metal coated with the DNA (cf. gene gun n. at gene n.2 Compounds 2); of or relating to such a procedure.
ΚΠ
1988 T. M. Klein et al. in Bio/technol. 6 559/2 By coating these microprojectiles with DNA, they can be used as a means for the transfer of foreign genetic material into intact cells and tissues. The utility of this biolistic (biological ballistic) process has been demonstrated for DNA delivery to the mitochondria and nucleus.
1997 Current Opinion in Biotechnol. 8 636/2 Another commonly used method for DNA-based immunization is the biolistic introduction of DNA-coated gold particles into the epidermis.
2001 New Scientist 24 Feb. 103/2 (advt.) The ideal candidate will have experience in grass/cereal tissue culture and be familiar with biolistic technology.
2007 S. Duvezin-Caubert et al. in I. Stansfield & M. J. R. Stark Yeast Gene Anal. (ed. 2) xix. 451 The genetic transformation of yeast mitochondria using the biolistic gun allowed researchers to create directed mutations.
This is a new entry (OED Third Edition, November 2010; most recently modified version published online December 2021).
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adj.1988