ryanodinen.

Brit.

/rʌɪˈanədiːn/, U.S.

/raɪˈænəˌdin/

Origin: A borrowing from Latin, combined with an English element. Etymons: Latin Ryania , -ine suffix⁵.

Etymology: < scientific Latin Ryania, name of a genus of tropical American plants ( M. H. Vahl Eclogae Americanae (1796) I. 51; < the name of John Ryan , 18th-cent. British physician and botanist + scientific Latin -ia -ia suffix¹) + -ine suffix⁵, with apparently arbitrary insertion of -od-.

Biochemistry and Physiology.

A poisonous alkaloid which occurs in the stems of the tropical American shrub Ryania speciosa (family Flacourtiaceae) and has been used as an insecticide and in experimental studies of calcium release within cells.Ryanodine is a diterpenoid with an esterified proline group. Formula: C₂₅H₃₅NO₉.

ΚΠ

1948 E. F. Rogers et al. in Jrnl. Amer. Chem. Soc. 70 3086/2 By repeated crystallization of this product from ether, a pure compound was obtained... This compound has been designated ryanodine.

1961 Biochem. Pharmacol. 8 36/2 The depressant effect of ryanodine on myocardial contractility..was examined.

1976 Star-News (Pasadena, Calif.) 2 Apr. 29/3 (advt.) Contains pyrethrins, Rotenone and Ryanodine.

1991 Nature 24 Jan. 337/1 Treatment of muscles with ryanodine, which induces Ca²⁺ release from the sarcoplasmic reticulum in the absence of activity, does not cause stabilization of junctional receptors.

2002 J. R. M. Thacker Introd. Arthropod Pest Control 37 Ryanodine is a contact and stomach poison that is more stable than many other botanical insecticides.

Compounds

ryanodine receptor n. a tetrameric protein complex, originally identified by its ability to bind ryanodine, which forms a channel for calcium release in intracellular membranes, esp. in the sarcoplasmic reticulum of muscle cells.

ΚΠ

1985 Biochem. & Biophysical Res. Communications 128 454 The high specificity of the ryanodine receptors is evident from displacement experiments with several ryanoids.

2008 N.Y. Times 12 Feb. (Washington Final ed.) d4/2 The investigators called the drugs rycals, because they attach to the ryanodine receptor/calcium release channel in heart muscle cells.

This is a new entry (OED Third Edition, March 2011; most recently modified version published online March 2022).

单词	ryanodine
释义	ryanodinen. Brit. /rʌɪˈanədiːn/, U.S. /raɪˈænəˌdin/ Origin: A borrowing from Latin, combined with an English element. Etymons: Latin Ryania , -ine suffix⁵. Etymology: < scientific Latin Ryania, name of a genus of tropical American plants ( M. H. Vahl Eclogae Americanae (1796) I. 51; < the name of John Ryan , 18th-cent. British physician and botanist + scientific Latin -ia -ia suffix¹) + -ine suffix⁵, with apparently arbitrary insertion of -od-. Biochemistry and Physiology. A poisonous alkaloid which occurs in the stems of the tropical American shrub Ryania speciosa (family Flacourtiaceae) and has been used as an insecticide and in experimental studies of calcium release within cells.Ryanodine is a diterpenoid with an esterified proline group. Formula: C₂₅H₃₅NO₉. ΚΠ 1948 E. F. Rogers et al. in Jrnl. Amer. Chem. Soc. 70 3086/2 By repeated crystallization of this product from ether, a pure compound was obtained... This compound has been designated ryanodine. 1961 Biochem. Pharmacol. 8 36/2 The depressant effect of ryanodine on myocardial contractility..was examined. 1976 Star-News (Pasadena, Calif.) 2 Apr. 29/3 (advt.) Contains pyrethrins, Rotenone and Ryanodine. 1991 Nature 24 Jan. 337/1 Treatment of muscles with ryanodine, which induces Ca²⁺ release from the sarcoplasmic reticulum in the absence of activity, does not cause stabilization of junctional receptors. 2002 J. R. M. Thacker Introd. Arthropod Pest Control 37 Ryanodine is a contact and stomach poison that is more stable than many other botanical insecticides. Compounds ryanodine receptor n. a tetrameric protein complex, originally identified by its ability to bind ryanodine, which forms a channel for calcium release in intracellular membranes, esp. in the sarcoplasmic reticulum of muscle cells. ΚΠ 1985 Biochem. & Biophysical Res. Communications 128 454 The high specificity of the ryanodine receptors is evident from displacement experiments with several ryanoids. 2008 N.Y. Times 12 Feb. (Washington Final ed.) d4/2 The investigators called the drugs rycals, because they attach to the ryanodine receptor/calcium release channel in heart muscle cells. This is a new entry (OED Third Edition, March 2011; most recently modified version published online March 2022). < n.1948
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