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单词 sabadine
释义

sabadinen.

/ˈsabədiːn/
Forms: Also † sabatine.
Etymology: < German sabadin (E. Merck 1891, in Arch. der Pharm. CCXXIX. 164): see sabadilla n. and -ine suffix5.
Biochemistry.
A veratrum alkaloid ester, C29H47NO8, present in sabadilla seeds.
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1891 Jrnl. Chem. Soc. 60 ii. 844 The author has isolated two alkaloïds from sabadilla seeds, Asagrœa officinalis. Sabadine is best separated as the nitrate.
1951 A. J. Hennig et al. in Jrnl. Amer. Pharmaceut. Assoc.: Sci. Ed. 40 168 Evidence has been obtained of at least five additional alkaloids in the water-soluble portion, crude fraction D..of sabadilla alkaloids. One of the new alkaloids has been obtained in crystalline state and given the name ‘sabatine’.
1962 Jrnl. Medicinal & Pharmaceut. Chem. 5 693 Sabatine was found to be identical with sabadine... On historical grounds, the names sabadine and sabine (for the ester and alkamine respectively) deserve preference.
1976 Jrnl. Neurochem. 27 1271/2 Veratrine sulfate consisted of the alkaloids veratridine, cevadilline, sabadine and cevadine.

Derivatives

sabadinine n. a crystalline principle, C27H45NO8, obtained from sabadilla.
ΚΠ
1891 Jrnl. Chem. Soc. 60 ii. 844 Sabadinine, C27H45NO8, does not melt at any definite temperature.
This entry has not yet been fully updated (first published 1933; most recently modified version published online December 2020).
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