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单词 actin
释义

actinn.

Brit. /ˈaktɪn/, U.S. /ˈæktən/
Origin: A borrowing from Greek, combined with an English element. Etymons: Greek ἀκτίς , -in suffix1.
Etymology: < ancient Greek ἀκτίς ray (see actino- comb. form) + -in suffix1.
Biochemistry.
A protein comprising globular subunits which aggregate to form filaments, originally identified (in association with myosin) as a component of muscle cells, and later found in almost all eukaryotic cells, being involved in cell shape, adhesion, and motility, and the motion of intracellular components.Aggregation of the globular actin (G-actin) monomer produces filaments (F-actin) in the form of a double helix. These form the microfilaments of the cytoskeleton, and are also the main component of the thin filaments of myofibrils.
ΚΠ
1942 A. Szent-Györgyi in Stud. Inst. Med. Chem. Univ. Szeged 1 67 Myosin B is a stoichiometric compound of myosin A and another substance. We will call this other substance ‘actin’.
1944 A. Szent-Györgyi Stud. on Muscle ii. 29 This property of actin, that it is capable of existing in two forms, in globular and fibrous form,..is striking and unique.
1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) vi. 786 Vinculin..anchors actin filaments of the cytoskeleton to the inside of the cell membrane.
1988 M. Perutz in I wish I'd made you Angry Earlier (2002) 135 When contraction is turned on, the actin filaments are drawn deeper into the spaces between the myosin filaments.
2007 Science 16 Mar. 1469/1 Organelles are carried long distances along microtubules by kinasin and then locally along actin tracks by myosin Va (myoVa).
This entry has been updated (OED Third Edition, November 2010; most recently modified version published online December 2021).
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n.1942
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