单词 | sotalol |
释义 | sotaloln. Pharmacology. The compound, CH3.NH(SO2).C6H4.CH(OH).CH2.NH.CH(CH3)2, a beta-adrenergic blocking agent used (in the form of its hydrochloride) in the treatment of cardiac arrhythmias. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs khellin1879 procainamide1950 pronethalol1963 propranolol1964 alprenolol1967 verapamil1967 oxprenolol1968 sotalol1968 perhexiline1969 practolol1969 beta-blocker1970 pindolol1971 acebutolol1972 mexiletine1973 atenolol1974 metoprolol1974 labetalol1975 propafenone1975 amrinone1977 1968 Jrnl. Pharmacol. & Exper. Therapeutics 160 231 The antiinflammatory action of morphine is reversed by nalorphine but not by a beta adrenergic blocking agent, sotalol (MJ 1999; 4-(2-isopropylamino-1-hydroxylethyl)-methanesulphonalinide hydrochloride). 1974 R. G. Shanks et al. in A. G. Snart Adv. in Beta-Adrenergic Blocking Therapy—Sotalol I. 24 Sotalol is the only drug which blocks all adrenergic β-receptors and has no membrane stabilizing activity or intrinsic sympathomimetic activity. 1978 Nature 19 Oct. 596/2 In contrast, β-adrenergic antagonists lacking the hydrophobicity of propranolol, such as atenolol, practolol and sotalol, are not able to induce meiosis. This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018). < n.1968 |
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