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单词 sotalol
释义

sotaloln.

/ˈsəʊtəlɒl/
Etymology: Etymology unknown: see -ol suffix.
Pharmacology.
The compound, CH3.NH(SO2).C6H4.CH(OH).CH2.NH.CH(CH3)2, a beta-adrenergic blocking agent used (in the form of its hydrochloride) in the treatment of cardiac arrhythmias.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs
khellin1879
procainamide1950
pronethalol1963
propranolol1964
alprenolol1967
verapamil1967
oxprenolol1968
sotalol1968
perhexiline1969
practolol1969
beta-blocker1970
pindolol1971
acebutolol1972
mexiletine1973
atenolol1974
metoprolol1974
labetalol1975
propafenone1975
amrinone1977
1968 Jrnl. Pharmacol. & Exper. Therapeutics 160 231 The antiinflammatory action of morphine is reversed by nalorphine but not by a beta adrenergic blocking agent, sotalol (MJ 1999; 4-(2-isopropylamino-1-hydroxylethyl)-methanesulphonalinide hydrochloride).
1974 R. G. Shanks et al. in A. G. Snart Adv. in Beta-Adrenergic Blocking Therapy—Sotalol I. 24 Sotalol is the only drug which blocks all adrenergic β-receptors and has no membrane stabilizing activity or intrinsic sympathomimetic activity.
1978 Nature 19 Oct. 596/2 In contrast, β-adrenergic antagonists lacking the hydrophobicity of propranolol, such as atenolol, practolol and sotalol, are not able to induce meiosis.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1968
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