spasmolyticadj.n.
/spazməˈlɪtɪk/ Pharmacology.
A. adj.
That relieves spasm of smooth muscle.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [adjective] > antispasmodic or anticonvulsant
antiepileptical1633
antiepileptic1655
anticonvulsive1696
spasmodic1728
antispasmodic1764
spasmolytic1937
anti-convulsant1946
muscle relaxant1951
1937 Jrnl. Pharmacol. & Exper. Therapeutics 60 13 The spasmolytic action of Syntropan exerted through the nerve endings on the isolated rabbit intestine is only about 20 times less than that of Atropine.
1953 Official Gaz. (U.S. Patent Office) 20 Oct. 564/2 Ciba Pharmaceutical Products, Inc... Serpasil. For sedative, hypotensive, and spasmolytic agent... Claims use since Mar. 17, 1953.
1964 W. G. Smith Allergy & Tissue Metabolism iv. 56 The effects of high dosage include ganglionic blockage and spasmolytic activity.
1982 Jrnl. Medicinal Chem. 25 1358/2 Some of these compounds have intensive spasmolytic activity for colonic motility.
B. n.
A spasmolytic drug.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant
antiepileptic1657
antispasmodic1681
spasmodics1704
anticonvellent1876
spasmolytic1937
anti-convulsant1943
anticonvulsive-
1937 Brit. Med. Jrnl. 11 Sept. 560/1 The employment of spasmolytics in obstetrics is useful.
1978 Acta Neurol. Scandinavica LVII. 65 The drug is..capable of depressing distressing clonus, and it is concluded that it deserves further testing as a spasmolytic.
Derivatives
spasˈmolysis n. the action of such drugs.
ΘΚΠ
the world > health and disease > healing > medical treatment > treatment by medicine or drug > [noun] > effects of medicines or drugs > effects of specific drugs
spasmolysis1946
1946 Biol. Abstr. 20 1122/1 Although the compounds..have some papaverine-like action on smooth muscle, spasmolysis results largely from their anticholinergic action.
1964 Jrnl. Amer. Geriatric Soc. 12 1083 (heading) Spasmolysis: a new technique for treatment of spasticity.
1977 Scandinavian Jrnl. Respiratory Dis. Suppl. No. 98. 47 (heading) Sensitization of contracted tracheal smooth muscle to β-adrenergic spasmolysis by subthreshold doses of papaverine.
This entry has not yet been fully updated (first published 1986; most recently modified version published online December 2020).
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adj.n.1937