单词 | statin |
释义 | statinn.1 Biochemistry and Physiology. A nuclear phosphoprotein that is present in non-replicating and senescent cells, but not in cells that are replicating. ΘΚΠ the world > life > biology > substance > proteins > [noun] casein1838 albuminoid1855 xanthoglobulin1868 myochrome1872 xanthoprotein1883 histone1885 globulose1886 phaseolin1893 leucosin1894 nucleohistone1894 nucleon1895 mucoid1898 protone1898 mucinoid1902 myohaemoglobin1906 nucleoprotamine1911 cytozyme1914 leaf protein1917 cytochrome1925 mucoprotein1925 myoglobin1925 flavoprotein1934 oxymyoglobin1935 ferritin1937 lipovitellin1942 arthropodin1947 trypticase1947 erythropoietin1948 phosvitin1948 opsin1951 orosomucoid1955 metallothionein1960 plastocyanin1961 aequorin1962 ferredoxin1962 LDL1962 fetoprotein1964 thioredoxin1964 actinin1965 adrenodoxin1965 lactoferrin1965 myoglobulin1965 rubredoxin1965 uniporter1967 miraculin1968 nexin1970 bacteriorhodopsin1971 molybdoprotein1971 monellin1972 cytokine1974 ankyrin1975 clathrin1975 electromorph1975 tau1975 uniport1975 microtrabecula1976 porin1976 osteocalcin1977 calmodulin1978 monokine1978 PCNA1978 vimentin1978 interleukin1979 laminin1979 titin1979 villin1979 cyclin1981 triskele1981 acumentin1982 perforin1983 statin1985 activin1986 addressin1988 synuclein1988 chemokine1992 1985 E. Wang in Jrnl. Cell Biol. 101 1695 (title) Rapid disappearance of statin, a nonproliferating and senescent cell-specific protein, upon reentering the process of cell cycling. 1992 Jrnl. Biol. Chem. 267 24067/2 Statin..is expressed in all terminally differentiated tissues, including liver and kidney. 2001 M. E. Warchol in A. F. Jahn & J. Santos-Sacchi Physiol. Ear (ed. 2) xii. 247/2 Statin expression in the cochlea is dramatically reduced after hair cell injury. This entry has been updated (OED Third Edition, December 2012; most recently modified version published online March 2022). statinn.2 Pharmacology. Any of a class of drugs that inhibit the action of an enzyme involved in cholesterol synthesis, esp. in the liver, and are used in the management of hypercholesterolaemia (an excess of cholesterol in the bloodstream).Statins are typically cyclic organic compounds such as lactones or pyrroles. ΚΠ 1987 Circulation 76 532/1 Lovastatin (formerly mevinolin) and synvinolin belong to the new group of statins, which lower serum cholesterol by stimulating removal of LDL via the LDL-receptor pathway. 1993 Independent on Sunday 22 Aug. (Weekend Suppl.) 42/5 The newest class of drugs are the ones called the statins, and there's a really startling increase in the rate at which they're being prescribed. 2010 Daily Tel. 31 Aug. 1/2 A study indicated that one third of patients who were switched from a branded statin to a cheaper generic one received a less powerful equivalent. This entry has been updated (OED Third Edition, December 2012; most recently modified version published online March 2022). < |
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