bolusn.

Brit.

/ˈbəʊləs/, U.S.

/ˈboʊləs/

Forms: Plural boluses: 1600s bolus, 1600s–1700s bolus's, 1700s–1800s bolusses.

Etymology: < modern Latin bōlus, < Greek βῶλος clod, lump of earth.

1. Medicine.

a. A medicine of round shape adapted for swallowing, larger than an ordinary pill. (Often used somewhat contemptuously.)

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines of specific form > pills, tablets, etc. > [noun] > pill > large pill

balla1400

bale1576

bole1601

bolus1603

1603 J. Florio tr. M. de Montaigne Ess. iii. ix. 588 I will not have a Bolus, or a glister.

1681 Table of Hard Words in S. Pordage tr. T. Willis Remaining Med. Wks. Bolus, is a medicine made up into a thick substance to be swallow'd not liquid, but taken on a knives point.

1751 W. Shenstone Wks. & Lett. III. 178 I have been taking saline draughts and bolus's.

1807 A. M. Porter Hungarian Brothers I. v. 126 Physic him to death with pills and boluses.

figurative.1637 Earl of Monmouth tr. V. Malvezzi Romulus & Tarquin 229 Cruell actions are so many bolus, which are never better taken than when wrapt up in gold.1780 W. Cowper Let. 3 May (1979) I. 334 Swallowing such bolusses as I send you.1878 W. Black Green Pastures iii. 23 Resolved not to swallow your Home Rule bolus.

b. A single dose of a drug, contrast medium, etc., introduced rapidly into a blood vessel.

ΘΚΠ

the world > health and disease > healing > medicines or physic > [noun] > dose of medicine > types of dose

overdose1700

under-dose1822

challenge1935

booster1950

loading dose1961

bolus1967

1967 Jrnl. Appl. Physiol. 22 497/2 A single bolus of 1.5–2.5μc ⁸⁴RbCl was injected rapidly into the superior vena cava.

1977 Lancet 20 Aug. 376/1 sGaw [sc. specific airways conductance] was measured 5 min after intravenous salbutamol sulphate (25 μg boluses) up to a cumulative dose of 300 μg.

1980 Brit. Med. Jrnl. 29 Mar. 922/2 All treatment was stopped and a bolus of 10ml of 10% calcium gluconate given.

2. A small rounded mass of any substance.

ΘΚΠ

the world > space > shape > curvature > curved three-dimensional shape or body > [noun] > sphericity or globularity > sphere > very small sphere or pellet

pellet1381

pillc1450

bullet1578

boulet1605

peloton1716

bolus1782

pilole-

1782 A. Monro Ess. Compar. Anat. (ed. 3) 23 in Monro's Anat. Human Bones (new ed.) The bolus would be in danger of falling out of the mouth.

1835 T. Hook Gilbert Gurney (1850) I. i. 3 A round mirror, encircled with gilt boluses.

1867 F. Francis Bk. Angling i. 7 A barley-meal bolus is the bait for roach.

1881 Sat. Rev. No. 1320. 206 One leaden bolus of the old ounce-of-lead pattern.

3. A kind of clay; = bole n.² 1.

ΘΚΠ

the world > the earth > structure of the earth > constituent materials > clay > [noun] > bole

bole1645

bolus1682

1682 N. Grew Exper. Luctation ii. ii. §2 in Anat. Plants 242 Bolus's are the Beds, or as it were, the Materia prima, both of opacous Stones, and Metals.

1863 S. Baring-Gould Iceland xii. 210 The soil is composed of soft bolus full of splinters of trachyte.

Derivatives

bolus-ways adv. as a bolus.

ΚΠ

1689 J. Moyle Abstr. Sea Chyrurg. Pref. If the Patient cannot take a Medecine in one form (as Bolus-waies).

Thesaurus »

Categories »

bolus-wise adv. = bolus-ways adv.

This entry has not yet been fully updated (first published 1887; most recently modified version published online December 2021).

单词	bolus
释义	bolusn. Brit. /ˈbəʊləs/, U.S. /ˈboʊləs/ Forms: Plural boluses: 1600s bolus, 1600s–1700s bolus's, 1700s–1800s bolusses. Etymology: < modern Latin bōlus, < Greek βῶλος clod, lump of earth. 1. Medicine. a. A medicine of round shape adapted for swallowing, larger than an ordinary pill. (Often used somewhat contemptuously.) ΘΚΠ the world > health and disease > healing > medicines or physic > medicines of specific form > pills, tablets, etc. > [noun] > pill > large pill balla1400 bale1576 bole1601 bolus1603 1603 J. Florio tr. M. de Montaigne Ess. iii. ix. 588 I will not have a Bolus, or a glister. 1681 Table of Hard Words in S. Pordage tr. T. Willis Remaining Med. Wks. Bolus, is a medicine made up into a thick substance to be swallow'd not liquid, but taken on a knives point. 1751 W. Shenstone Wks. & Lett. III. 178 I have been taking saline draughts and bolus's. 1807 A. M. Porter Hungarian Brothers I. v. 126 Physic him to death with pills and boluses. figurative.1637 Earl of Monmouth tr. V. Malvezzi Romulus & Tarquin 229 Cruell actions are so many bolus, which are never better taken than when wrapt up in gold.1780 W. Cowper Let. 3 May (1979) I. 334 Swallowing such bolusses as I send you.1878 W. Black Green Pastures iii. 23 Resolved not to swallow your Home Rule bolus. b. A single dose of a drug, contrast medium, etc., introduced rapidly into a blood vessel. ΘΚΠ the world > health and disease > healing > medicines or physic > [noun] > dose of medicine > types of dose overdose1700 under-dose1822 challenge1935 booster1950 loading dose1961 bolus1967 1967 Jrnl. Appl. Physiol. 22 497/2 A single bolus of 1.5–2.5μc ⁸⁴RbCl was injected rapidly into the superior vena cava. 1977 Lancet 20 Aug. 376/1 sGaw [sc. specific airways conductance] was measured 5 min after intravenous salbutamol sulphate (25 μg boluses) up to a cumulative dose of 300 μg. 1980 Brit. Med. Jrnl. 29 Mar. 922/2 All treatment was stopped and a bolus of 10ml of 10% calcium gluconate given. 2. A small rounded mass of any substance. ΘΚΠ the world > space > shape > curvature > curved three-dimensional shape or body > [noun] > sphericity or globularity > sphere > very small sphere or pellet pellet1381 pillc1450 bullet1578 boulet1605 peloton1716 bolus1782 pilole- 1782 A. Monro Ess. Compar. Anat. (ed. 3) 23 in Monro's Anat. Human Bones (new ed.) The bolus would be in danger of falling out of the mouth. 1835 T. Hook Gilbert Gurney (1850) I. i. 3 A round mirror, encircled with gilt boluses. 1867 F. Francis Bk. Angling i. 7 A barley-meal bolus is the bait for roach. 1881 Sat. Rev. No. 1320. 206 One leaden bolus of the old ounce-of-lead pattern. 3. A kind of clay; = bole n.² 1. ΘΚΠ the world > the earth > structure of the earth > constituent materials > clay > [noun] > bole bole1645 bolus1682 1682 N. Grew Exper. Luctation ii. ii. §2 in Anat. Plants 242 Bolus's are the Beds, or as it were, the Materia prima, both of opacous Stones, and Metals. 1863 S. Baring-Gould Iceland xii. 210 The soil is composed of soft bolus full of splinters of trachyte. Derivatives bolus-ways adv. as a bolus. ΚΠ 1689 J. Moyle Abstr. Sea Chyrurg. Pref. If the Patient cannot take a Medecine in one form (as Bolus-waies). Thesaurus » Categories » bolus-wise adv. = bolus-ways adv. This entry has not yet been fully updated (first published 1887; most recently modified version published online December 2021). < n.1603
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