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单词 subacute sclerosing panencephalitis
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subacute sclerosing panencephalitis
Inflammation of white and grey matter of the brain; diffuse or generalized encephalitis; an instance of this; spec. (in full subacute sclerosing panencephalitis) a chronic diffuse encephalitis causing progressive neurological deterioration and death, seen as a rare complication of measles virus infection, usually in children.
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the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > inflammation of brain > encephalitis > types of
meningoencephalomyelitis1900
chronic fatigue1908
leucoencephalitis1909
sleeping sickness1918
X disease1918
sleepy sickness1922
western equine encephalitis1933
St. Louis encephalitis1934
Russian encephalitis1940
panencephalitis1950
Murray Valley encephalitis1951
Iceland disease1954
Murray Valley fever1955
myalgic encephalomyelitis1956
ME1982
1950 Brain 73 150 Perhaps the term ‘Pan-encephalitis’ already adopted by Pette (1942) for forms which attack both grey and white matter could be usefully employed here, i.e. ‘Sub-acute sclerosing pan-encephalitis’.
1968 Arch. Neurol. 18 563 (title) Acute malacic and liquefying panencephalitis caused by an agent recovered from Burkitt's lymphoma.
1974 Sci. Amer. Feb. 35/1 In 1969..measles virus was isolated from brain cells of patients suffering from the brain inflammation called subacute sclerosing panencephalitis (SSPE).
1996 Infection 24 332 Two days later she developed an acute HIV infection presenting as a fulminant multisystem disease that lasted for 35 hospital days and included:..peripheral neuropathy with myopathy, and panencephalitis.
2002 Guardian 26 July ii. 15/5 Children under the age of one are much more at risk from a complication of measles called sub-acute sclerosing panencephalitis.
extracted from panencephalitisn.
subacute sclerosing panencephalitis
subacute sclerosing panencephalitis n. Medicine a rare, usually fatal disorder caused by persistent measles virus infection, typically occurring in children or adolescents within 3 to 10 years after the initial measles infection and characterized by inflammation and degeneration of both grey and white matter of the brain, resulting in behavioural and neurological symptoms; abbreviated SSPE.
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1950 J. G. Greenfield in Brain 73 150 The name subacute sclerosing encephalitis therefore appears fully justified. Dr. van Bogaert's term ‘leuco-encephalitis’ emphasizes the characteristic damage to the white matter, but leaves out of account the cortical changes which are also important. Perhaps the term ‘Panencephalitis’ already adopted by Pette (1942) for forms which attack both grey and white matter could be usefully employed here, i.e. ‘Subacute sclerosing panencephalitis’.
1967 Brit. Med. Jrnl. 5 Aug. 352/2 Measles complement-fixing and haemagglutination-inhibiting antibodies have been found in the serum of 22 patients with subacute sclerosing panencephalitis in significantly higher titre.
2001 Guardian 26 July ii. 15/5 Children under the age of one are much more at risk from a complication of measles called sub-acute sclerosing panencephalitis.
extracted from subacuteadj.
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