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1887 Pop. Sci. Monthly Sept. 613 We talk most about specialties in medicine, for the very reason that it was one of the last occupations to be sub-specialized.

1900 Congregationalist (Boston, Mass.) 8 Feb. 182/1 He anticipated the modern method of specialization first by separating the Bible from other books,..and, second, by sub-specializing on the Bible itself.

1955 Econ. Devel. & Cultural Change 4 153 Weavers of various articles and in various materials, also subspecialized according to specific textile product.

2011 B. J. Hillman & J. C. Goldsmith Sorcerer's Apprentice x. 240 Radiologists are increasingly subspecializing, furthering their participation in this type of multidisciplinary care.

2012 R. Holmgaard et al. in H. A. E. Benson & A. C. Watkinson Topical & Transdermal Drug Delivery vii. 132 Subsequently, the technique was subspecialized and it is currently used in many different tissues in animal models as well as in human studies.