单词 | sulphamethoxazole |
释义 | > as lemmasˌsulphameˈthoxazole ˌsulphameˈthoxazole n. [meth- (in methyl n.) + isoxazole n. at iso- comb. form 2b] the sulphonamide CH3·C3HNO·NH·SO2·C6H4·NH2, used in the treatment of respiratory and urinary tract infections, and as a component of the preparation co-trimoxazole; N1-(5-methylisoxazol-3-yl)sulphanilamide. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bacteriostatic > sulphonamide > specific Prontosil1935 Prontosil soluble1936 Albucid1938 Prontosil red1938 sulphapyridine1939 sulphathiazole1939 sulphadiazine1940 succinylsulphathiazole1941 sulphacetamide1941 sulphaguanidine1941 sulphamethazine1942 phthalylsulphathiazole1943 sulfamerazine1943 Sulphamezathine1943 Sulphatriad1948 sulphadimidine1950 sulphamethizole1952 sulphisoxazole1952 sulphamethoxypyridazine1956 sulphamethoxazole1960 sulphafurazole1961 sulphasalazine- 1960 Antibiotics & Chemotherapy (N.Y.) X. 572 A new sulfonamide compound, sulfamethoxazole, is identified chemically as 5-methyl-3-sulfanilamidoisoxazole. 1977 Lancet 2 July 4/1 Much of the shigellosis could be successfully treated with ampicillin trihydrate and closely related antibiotics, or with co-trimoxazole (trimethoprim and sulphamethoxazole). 1981 H. J. Rogers et al. Textbk. Clin. Pharmacol. xix. 653 Sulphamethoxazole is about 50% metabolised so that much reaches the urine in an inactive form. < as lemmas |
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