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单词 sulphanilamide
释义

sulphanilamidesulfanilamiden.

/sʌlfəˈnɪləmaɪd/
Forms: Also (U.S.) sulf-.
Etymology: < sulphanilic adj. at sulph- comb. form 1 ( < anil- (in aniline n.) + -ic suffix) + amide n.
Pharmacol.
a. The amide of sulphanilic acid, which has wide bacteriostatic activity, has been used, esp. topically, in the treatment of infections due to hæmolytic streptococci, and is the parent compound of the sulphonamides; p-aminobenzenesulphonamide, H2N·C6H4·SO2·NH2.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bacteriostatic > sulphonamide > sulphanilamide
Prontosil album1937
sulphanilamide1937
sulpha1942
1937 Jrnl. Amer. Med. Assoc. 17 Apr. 1340/2 The Council [on Pharmacy and Chemistry] has therefore formally adopted the nonproprietary name ‘Sulfanilamide’ for para-aminobenzenesulfonamide.
1942 Times 9 Oct. 2/4 A further long list of requirements was sent back from Moscow... The articles dispatched..have included:—530,000 blankets,..10,000 kilos sulphanilamide.
1953 M. Lowry Let. 31 Oct. (1967) 345 The chief engineer has an ulcerated throat, and the ship itself is running on sulfanilamide.
1962 J. Heller Catch-22 xli. 428 Snowden..shifted the position of his hips a bit so that Yossarian could begin salting the wound with sulfanilamide.
1967 Martindale's Extra Pharmacopoeia (ed. 25) 1376/1 Sulfphanilamide,..together with the earlier derivatives, sulphapyridine and sulphathiazole, has been largely superseded by more effective and less toxic compounds.
1974 R. M. Kirk et al. Surgery ii. 27 Sulphanilamide powder is sometimes used topically on raw surfaces, in abscess cavities and body spaces such as the peritoneal and pleural cavities.
b. Any substituted derivative of this compound.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bacteriostatic > sulphonamide > sulphanilamide > derivatives
Sulfasuxidine1942
sulphanilamide1961
1961 Webster's 3rd New Internat. Dict. Eng. Lang.
1962 H. A. Krebs in A. Pirie Lens Metabolism 351 The effects..of sulphanilamides on the metabolism of p-aminobenzoic acid.
This entry has not yet been fully updated (first published 1986; most recently modified version published online November 2010).
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n.1937
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