sulphinpyrazonesulfinpyrazonen.
Pharmacol.
The uricosuric drug C6H5·SO·(CH3)CH·C3HN2O2(C6H5)2, which promotes excretion of urates by inhibiting their reabsorption by kidneys; 1,2-diphenyl-4-(2-phenylsulphinylethyl)pyrazolidine-3, 5-dione.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > uricosuric or saluretic
probenecid1950
sulphinpyrazone1958
saluretic1975
1958 Arthritis & Rheumatism I. 532 The present communication is concerned with G-28315 (4-[phenylsulfoxyethyl]-1,2-diphenyl-3,5-pyrazolidinedione). [Note] The generic name of this compound is sulfinpyrazone.
1961 Lancet 30 Sept. 763/2 Aspirin..could within a few days overcome the effects for which probenecid, sulfinpyrazone, or zoxazolamine had been prescribed.
1978 Times 2 Mar. 16/6 The American research project was set up to test the theory that the risk of this further thrombosis might be reduced by treatment with a drug, sulfinpyrazone, which acts on the blood platelets, the small cells that start the process of thrombosis.
1981 H. J. Rogers et al. Textbk. Clin. Pharmacol. xvii. 569 Sulphinpyrazone (Anturan)..is a uricosuric drug related to phenylbutazone which prolongs platelet survival..without prolonging the bleeding time.
This entry has not yet been fully updated (first published 1986; most recently modified version published online November 2010).
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n.1958