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单词 suramin sodium
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suramin sodium
A complex symmetric urea used in the treatment of trypanosomiasis and filariasis. Also suramin sodium.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides > specific drugs
phenanthridine1890
trypan red1905
trypan blue1911
tryparsamide1921
Bayer 2051922
stibophen1941
stilbamidine1941
suramin1941
mepacrine1943
PABA1943
metronidazole1960
stibocaptate1962
1941 Brit. Pharmacopœia 1932 Add. iv. 33 Suramin is the symmetrical urea of the sodium salt of m-benzoyl-m-amino-p-methylbenzoyl-1-aminonaphthalene-4:6:8-trisulphonic acid.
1951 A. Grollman Pharmacol. & Therapeutics xx. 416 Atoxyl..was the first drug used successfully in trypanosomiasis. Tryparsamide..was an improvement and with Suramin..is effective in the treatment of the early stage of the disease before the organisms appear in the spinal fluid.
1974 Encycl. Brit. Micropædia IX. 687/3 Suramin sodium, a white or pinkish powder soluble in water, is administered in an aqueous or saline solution.
1978 Nature 22 June 627/1 Three antitrypanosomal drugs are listed by the WHO as essential for the treatment of human sleeping sickness caused by African trypanosomiasis. They are melarsoprol (Mel B), pentamidine (Lomidine) and suramin (Antrypol, Germanin).
extracted from suraminn.
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