单词 | suramin sodium |
释义 | > as lemmassuramin sodium A complex symmetric urea used in the treatment of trypanosomiasis and filariasis. Also suramin sodium. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides > specific drugs phenanthridine1890 trypan red1905 trypan blue1911 tryparsamide1921 Bayer 2051922 stibophen1941 stilbamidine1941 suramin1941 mepacrine1943 PABA1943 metronidazole1960 stibocaptate1962 1941 Brit. Pharmacopœia 1932 Add. iv. 33 Suramin is the symmetrical urea of the sodium salt of m-benzoyl-m-amino-p-methylbenzoyl-1-aminonaphthalene-4:6:8-trisulphonic acid. 1951 A. Grollman Pharmacol. & Therapeutics xx. 416 Atoxyl..was the first drug used successfully in trypanosomiasis. Tryparsamide..was an improvement and with Suramin..is effective in the treatment of the early stage of the disease before the organisms appear in the spinal fluid. 1974 Encycl. Brit. Micropædia IX. 687/3 Suramin sodium, a white or pinkish powder soluble in water, is administered in an aqueous or saline solution. 1978 Nature 22 June 627/1 Three antitrypanosomal drugs are listed by the WHO as essential for the treatment of human sleeping sickness caused by African trypanosomiasis. They are melarsoprol (Mel B), pentamidine (Lomidine) and suramin (Antrypol, Germanin). < as lemmas |
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