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单词 tetracosactrin
释义

tetracosactrinn.

/ˌtɛtrəkɒˈsaktrɪn/
Etymology: < tetra- comb. form + -cos (in icos- comb. form) + a- + -c- + -tr- + -in (in adrenocorticotropin n.).
Pharmacology.
A synthetic polypeptide (see quot. 1967) which resembles corticotrophin in its action and uses but lacks its antigenic property, and is given (as the acetate) by injection in the long-term treatment of inflammatory and degenerative disorders.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological
hydroxycorticosterone1943
hydrocortisone1951
cortisol1953
prednisolone1955
prednisone1955
triamcinolone1957
mefenamic acid1962
ibuprofen1967
tetracosactrin1967
1967 Brit. Med. Jrnl. 18 Nov. 391/1 Tetracosactrin1−24 corticotrophin, Synacthen) is a synthetic poly~peptide containing the first 24 amino-acids found in naturally occurring corticotrophin (A.C.T.H.).
1972 Brit. Med. Jrnl. 11 Mar. 680/1 The pathognomic finding is their failure [sc. that of urinary and plasma corticosteroids] to show a rise after the administration of ACTH or tetracosactrin.
1979 Jrnl. Royal Soc. Med. 72 530 A tetracosactrin (Synacthen) stimulation test.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1967
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