单词 | tetracosactrin |
释义 | tetracosactrinn. Pharmacology. A synthetic polypeptide (see quot. 1967) which resembles corticotrophin in its action and uses but lacks its antigenic property, and is given (as the acetate) by injection in the long-term treatment of inflammatory and degenerative disorders. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological hydroxycorticosterone1943 hydrocortisone1951 cortisol1953 prednisolone1955 prednisone1955 triamcinolone1957 mefenamic acid1962 ibuprofen1967 tetracosactrin1967 1967 Brit. Med. Jrnl. 18 Nov. 391/1 Tetracosactrin (β1−24 corticotrophin, Synacthen) is a synthetic poly~peptide containing the first 24 amino-acids found in naturally occurring corticotrophin (A.C.T.H.). 1972 Brit. Med. Jrnl. 11 Mar. 680/1 The pathognomic finding is their failure [sc. that of urinary and plasma corticosteroids] to show a rise after the administration of ACTH or tetracosactrin. 1979 Jrnl. Royal Soc. Med. 72 530 A tetracosactrin (Synacthen) stimulation test. This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018). < n.1967 |
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