thiaminen.

Brit.

/ˈθʌɪəmiːn/,

/ˈθʌɪəmɪn/, U.S.

/θaɪˈæmən/,

/ˈθaɪəˌmin/,

/ˈθaɪəmən/

Etymology: < thi- (in thio- comb. form) + amine n.

†1. Chemistry. (See quot.) Obsolete. rare.

ΘΚΠ

the world > matter > chemistry > organic chemistry > organic dyes > [noun] > colour unspecified

thiamine1887

thiazine1893

1887 C. A. Bennert Brit. Patent 13,466/1886 3 This invention has for its object the manufacture or production of a new class of organic coloring compounds or materials by reactions between certain amines of the aromatic series and the dioxide of sulphur group, which organic colouring compounds or materials so obtained I designate ‘Thiamines’.

Categories »

†2. Chemistry. Generic name for amines containing the group NHSH, as ethylthiamine, C₂H₅.NHSH. Obsolete. rare.

3. Biochemistry.

a. Also thiamin. Vitamin B₁; a water-soluble, heat-labile, sulphur-containing compound that is present in many foods (esp. whole cereal grains, pork, and liver) but absent from fats and is necessary for carbohydrate metabolism, its dietary deficiency resulting in disturbances of the nervous system.

ΚΠ

1937 Jrnl. Amer. Med. Assoc. 18 Sept. 952/1 Dr. Jansen has been very cooperative in discussing the matter of nomenclature for vitamin B1 and suggested..that Dr. R. R. Williams..propose a name based on the chemical structure. Dr. Williams..proposed the term Thiamin Chloride.

1939 A. Huxley After Many a Summer ii. vi. 234 With a course of thiamin chloride and some testosterone I could have made him as happy as a sand-boy.

1951 A. Grollman Pharmacol. & Therapeutics xxvii. 597 Thiamine contains thiazole and pyrimidine rings.

1952 New Biol. 13 111 The role of thiamin in cell metabolism is to provide a portion of certain enzyme systems.

1972 Materials & Technol. V. xix. 674 In Great Britain, all bread except wholemeal must be fortified with thiamin..to compensate for the losses of the natural vitamin consequent on milling.

1980 D. Madden Food & Nutrition i. 23/2 After vitamin C, thiamine is probably the most unstable vitamin.

b. thiamine pyrophosphate n. the active form of thiamine in which it acts as a co-enzyme: = cocarboxylase n.

ΚΠ

1949 New Biol. 7 108 These include thiamine pyrophosphate, nicotinamide nucleoside and riboflavine, all of which are involved in systems through which carbohydrates are oxidised.

1960 A. E. Bender Dict. Nutrition & Food Technol. 32/2 Cocarboxylase is the diphosphate of vitamin B₁, alternatively known as thiamine pyrophosphate or diphosphothiamine.

1973 M. Yudkin & R. Offord Comprehensive Biochem. (1980) xvii. 297 Transketolase needs as co-factor the vitamin derivative thiamine pyrophosphate, which..is also involved in the transfer of a two-carbon fragment from pyruvate to lipoic acid.

Derivatives

thiˈaminase n. [-ase suffix] an enzyme that destroys thiamine, splitting the thiazole and the pyrimidine rings.

ΚΠ

1938 Bonner & Buchman in Proc. National Acad. Sci. U.S.A. 24 437 It has been shown..that the pea root synthesizes vitamin B₁..from a mixture of the pyrimidine and thiazole components of the vitamin molecule... This must..be a synthesis in which a specific enzyme, a ‘thiaminase’.., takes part.

1972 L. Hancock There's a Seal in my Sleeping Bag ii. 23 Herring is a fish that contains an enzyme called thiaminase, which breaks down thiamin in the body.

This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2022).

单词	thiamine
释义	thiaminen. Brit. /ˈθʌɪəmiːn/, /ˈθʌɪəmɪn/, U.S. /θaɪˈæmən/, /ˈθaɪəˌmin/, /ˈθaɪəmən/ Etymology: < thi- (in thio- comb. form) + amine n. †1. Chemistry. (See quot.) Obsolete. rare. ΘΚΠ the world > matter > chemistry > organic chemistry > organic dyes > [noun] > colour unspecified thiamine1887 thiazine1893 1887 C. A. Bennert Brit. Patent 13,466/1886 3 This invention has for its object the manufacture or production of a new class of organic coloring compounds or materials by reactions between certain amines of the aromatic series and the dioxide of sulphur group, which organic colouring compounds or materials so obtained I designate ‘Thiamines’. Categories » †2. Chemistry. Generic name for amines containing the group NHSH, as ethylthiamine, C₂H₅.NHSH. Obsolete. rare. 3. Biochemistry. a. Also thiamin. Vitamin B₁; a water-soluble, heat-labile, sulphur-containing compound that is present in many foods (esp. whole cereal grains, pork, and liver) but absent from fats and is necessary for carbohydrate metabolism, its dietary deficiency resulting in disturbances of the nervous system. ΚΠ 1937 Jrnl. Amer. Med. Assoc. 18 Sept. 952/1 Dr. Jansen has been very cooperative in discussing the matter of nomenclature for vitamin B1 and suggested..that Dr. R. R. Williams..propose a name based on the chemical structure. Dr. Williams..proposed the term Thiamin Chloride. 1939 A. Huxley After Many a Summer ii. vi. 234 With a course of thiamin chloride and some testosterone I could have made him as happy as a sand-boy. 1951 A. Grollman Pharmacol. & Therapeutics xxvii. 597 Thiamine contains thiazole and pyrimidine rings. 1952 New Biol. 13 111 The role of thiamin in cell metabolism is to provide a portion of certain enzyme systems. 1972 Materials & Technol. V. xix. 674 In Great Britain, all bread except wholemeal must be fortified with thiamin..to compensate for the losses of the natural vitamin consequent on milling. 1980 D. Madden Food & Nutrition i. 23/2 After vitamin C, thiamine is probably the most unstable vitamin. b. thiamine pyrophosphate n. the active form of thiamine in which it acts as a co-enzyme: = cocarboxylase n. ΚΠ 1949 New Biol. 7 108 These include thiamine pyrophosphate, nicotinamide nucleoside and riboflavine, all of which are involved in systems through which carbohydrates are oxidised. 1960 A. E. Bender Dict. Nutrition & Food Technol. 32/2 Cocarboxylase is the diphosphate of vitamin B₁, alternatively known as thiamine pyrophosphate or diphosphothiamine. 1973 M. Yudkin & R. Offord Comprehensive Biochem. (1980) xvii. 297 Transketolase needs as co-factor the vitamin derivative thiamine pyrophosphate, which..is also involved in the transfer of a two-carbon fragment from pyruvate to lipoic acid. Derivatives thiˈaminase n. [-ase suffix] an enzyme that destroys thiamine, splitting the thiazole and the pyrimidine rings. ΚΠ 1938 Bonner & Buchman in Proc. National Acad. Sci. U.S.A. 24 437 It has been shown..that the pea root synthesizes vitamin B₁..from a mixture of the pyrimidine and thiazole components of the vitamin molecule... This must..be a synthesis in which a specific enzyme, a ‘thiaminase’.., takes part. 1972 L. Hancock There's a Seal in my Sleeping Bag ii. 23 Herring is a fish that contains an enzyme called thiaminase, which breaks down thiamin in the body. This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2022). < n.1887
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