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单词 thioguanine
释义

> as lemmas

thioguanine
thioguanine n.
Brit. /ˌθʌɪə(ʊ)ˈɡwɑːniːn/
,
U.S. /ˌθaɪoʊˈɡwɑˌnin/
a thio analogue of guanine with cytotoxic properties, given orally in the treatment of leukaemia.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia
amethopterin1948
Myleran1952
Laetrile1953
thioguanine1953
thioTEPA1953
mercaptopurine1954
methotrexate1955
busulfan1956
chlorambucil1956
cyclophosphamide1960
vinblastine1962
vincristine1962
levamisole1969
vinca alkaloid1970
doxorubicin1971
tamoxifen1972
Airol1974
trastuzumab1997
thiotepa-
1953 Jrnl. Biol. Chem. 204 38 The preparation of thioguanine completely free from guanine has proved difficult.
1962 Jrnl. Amer. Med. Assoc. 10 Mar. 791/1 The drug used in this study, 6-thioguanine, is an adenine analogue closely related to 6-mercaptopurine.
1977 Cancer 40 998/1 The introduction of cytosine arabinoside..and 6-thioguanine..significantly improved the therapy of AML [sc. acute myeloblastic leukaemia] in adults.
1988 New Scientist 22 Oct. 27/2 These drugs, 6-mercaptopurine and thioguanine, are still used in the treatment of leukaemia.
extracted from thio-comb. form
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as lemmas
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