thrombolyticadj.n.

Brit.

/ˌθrɒmbə(ʊ)ˈlɪtɪk/, U.S.

/ˌθrɑmboʊˈlɪdɪk/,

/ˌθrɑmbəˈlɪdɪk/

Origin: Formed within English, by compounding. Etymons: thrombo- comb. form, -lytic comb. form.

Etymology: < thrombo- comb. form + -lytic comb. form. Compare French thrombolytique (1910 or earlier).

Medicine.

A. adj.

Of or relating to thrombolysis; causing thrombolysis. Cf. clot-busting adj. at clot n. Additions.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [adjective] > for the blood

anti-coagulant1905

thrombolytic1914

1914 Lancet 28 Mar. 882/1 The contents of the vagina consist of the products of thrombolytic and hæmolytic digestion, mixed with vaginal cells and the secretions of the corporeal and cervical glands.

1921 Brit. Med. Jrnl. 10 Dec. 982/2 As soon as the uterine glands stop secreting, the thrombolytic factor ceases, and the endometrial vessels are immediately closed by rapid physiological thrombosis.

1962 Amer. Jrnl. Med. 33 738/1 The adjective ‘thrombolytic’ will be used to designate biochemical moieties capable of inducing thrombolysis.

1971 Times 6 Aug. 4/1 The thrombolytic treatment [with streptokinase] was assessed in 700 patients in eight hospital centres.

2016 Hamilton (Ont.) Spectator (Nexis) 16 June a1 It takes 37 minutes from the time a patient having a stroke caused by a blood clot arrives at hospital to when acute thrombolytic therapy..is given.

B. n.

A thrombolytic agent. Cf. clot-buster n. at clot n. Additions.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > thrombolytics

urokinase1952

thrombolytic1965

ancrod1970

1965 Zeitschr. f. die gesamte innere Med. 20 720/2 The thrombolytics really have enriched the palette of antithrombotics.

1974 R. M. Kirk in R. M. Kirk et al. Surgery ii. 14/1 The thrombus may be removed surgically; at present this is less expensive than giving thrombolytics.

1991 Brit. Med. Jrnl. 28 Sept. 784/3 The benefit conferred by giving a thrombolytic was dramatically better than that of not giving it (a 60-fold advantage) whenever myocardial infarction was suspected.

2005 Sci. Amer. (U.K. ed.) Aug. 12/3 MRI and CT imaging may also identify those at risk for bleeding if given thrombolytics, a concern that keeps some physicians from administering tPA [= tissure plasminogen activator] even within three hours.

This entry has been updated (OED Third Edition, March 2017; most recently modified version published online June 2022).

单词	thrombolytic
释义	thrombolyticadj.n. Brit. /ˌθrɒmbə(ʊ)ˈlɪtɪk/, U.S. /ˌθrɑmboʊˈlɪdɪk/, /ˌθrɑmbəˈlɪdɪk/ Origin: Formed within English, by compounding. Etymons: thrombo- comb. form, -lytic comb. form. Etymology: < thrombo- comb. form + -lytic comb. form. Compare French thrombolytique (1910 or earlier). Medicine. A. adj. Of or relating to thrombolysis; causing thrombolysis. Cf. clot-busting adj. at clot n. Additions. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [adjective] > for the blood anti-coagulant1905 thrombolytic1914 1914 Lancet 28 Mar. 882/1 The contents of the vagina consist of the products of thrombolytic and hæmolytic digestion, mixed with vaginal cells and the secretions of the corporeal and cervical glands. 1921 Brit. Med. Jrnl. 10 Dec. 982/2 As soon as the uterine glands stop secreting, the thrombolytic factor ceases, and the endometrial vessels are immediately closed by rapid physiological thrombosis. 1962 Amer. Jrnl. Med. 33 738/1 The adjective ‘thrombolytic’ will be used to designate biochemical moieties capable of inducing thrombolysis. 1971 Times 6 Aug. 4/1 The thrombolytic treatment [with streptokinase] was assessed in 700 patients in eight hospital centres. 2016 Hamilton (Ont.) Spectator (Nexis) 16 June a1 It takes 37 minutes from the time a patient having a stroke caused by a blood clot arrives at hospital to when acute thrombolytic therapy..is given. B. n. A thrombolytic agent. Cf. clot-buster n. at clot n. Additions. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > thrombolytics urokinase1952 thrombolytic1965 ancrod1970 1965 Zeitschr. f. die gesamte innere Med. 20 720/2 The thrombolytics really have enriched the palette of antithrombotics. 1974 R. M. Kirk in R. M. Kirk et al. Surgery ii. 14/1 The thrombus may be removed surgically; at present this is less expensive than giving thrombolytics. 1991 Brit. Med. Jrnl. 28 Sept. 784/3 The benefit conferred by giving a thrombolytic was dramatically better than that of not giving it (a 60-fold advantage) whenever myocardial infarction was suspected. 2005 Sci. Amer. (U.K. ed.) Aug. 12/3 MRI and CT imaging may also identify those at risk for bleeding if given thrombolytics, a concern that keeps some physicians from administering tPA [= tissure plasminogen activator] even within three hours. This entry has been updated (OED Third Edition, March 2017; most recently modified version published online June 2022). < adj.n.1914
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