thyroxinen.

/θʌɪəˈrɒksiːn/

Forms: Also thyroxin.

Etymology: < thyr- (in thyro- comb. form) + -ox- (in oxy- comb. form²) + -in (in indole n.), after the original (erroneous) description of its chemical composition: see quot. 1918.

Biochemistry.

A hormone secreted by the thyroid gland which increases the metabolic rate and regulates growth and development in animals; tetraiodothyronine, HO·C₆H₂I₂·O·C₆H₂I₂·CH₂CH(NH₂)COOH.

ΚΠ

1918 E. C. Kendall in Endocrinology II. 90 It appeared desirable to emphasize the presence of the oxy-indol nucleus and it appeared equally desirable not to emphasize the presence of iodin. The substance was therefore named ‘Thyro-oxy-indol’, which has been shortened to ‘thyroxin’ for every-day reference to the substance.

1926 C. R. Harington in Biochem. Jrnl. 20 294 It is impossible to accept the formula proposed by Kendall, and..the constitution of thyroxine must be regarded as not proven.

1969 Daily Tel. 19 Dec. 11/7 Thyroxine, given to thyroid-deficient babies and adults, saves them from cretinism and myxoedema.

1979 K. Arms & P. S. Camp Biol. xxx. 501 If the tail is removed from a tadpole and placed in a bath containing thyroxin, the white blood cells in the tail will digest it.

This entry has not yet been fully updated (first published 1933; most recently modified version published online December 2020).

单词	thyroxine
释义	thyroxinen. /θʌɪəˈrɒksiːn/ Forms: Also thyroxin. Etymology: < thyr- (in thyro- comb. form) + -ox- (in oxy- comb. form²) + -in (in indole n.), after the original (erroneous) description of its chemical composition: see quot. 1918. Biochemistry. A hormone secreted by the thyroid gland which increases the metabolic rate and regulates growth and development in animals; tetraiodothyronine, HO·C₆H₂I₂·O·C₆H₂I₂·CH₂CH(NH₂)COOH. ΚΠ 1918 E. C. Kendall in Endocrinology II. 90 It appeared desirable to emphasize the presence of the oxy-indol nucleus and it appeared equally desirable not to emphasize the presence of iodin. The substance was therefore named ‘Thyro-oxy-indol’, which has been shortened to ‘thyroxin’ for every-day reference to the substance. 1926 C. R. Harington in Biochem. Jrnl. 20 294 It is impossible to accept the formula proposed by Kendall, and..the constitution of thyroxine must be regarded as not proven. 1969 Daily Tel. 19 Dec. 11/7 Thyroxine, given to thyroid-deficient babies and adults, saves them from cretinism and myxoedema. 1979 K. Arms & P. S. Camp Biol. xxx. 501 If the tail is removed from a tadpole and placed in a bath containing thyroxin, the white blood cells in the tail will digest it. This entry has not yet been fully updated (first published 1933; most recently modified version published online December 2020). < n.1918
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