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thromboplastin
thromboplastin n.
Brit. 
/ˌθrɒmbə(ʊ)ˈplastɪn/
, /ˌθrɒmbə(ʊ)ˈplastɪn/U.S. /ˌθrɑmboʊˈplæstən/
a thromboplastic substance, esp. one that plays a role in the activation of thrombin; spec. (more fully tissue thromboplastin) a protein produced in tissues outside the vascular system that plays such a role (also called tissue factor)./ˌθrɑmboʊˈplæstən/ΚΠ
1911 W. H. Howell in Amer. Jrnl. Physiol. 29 189 They [sc. tissue extracts] furnish a substance, which may be designated as a thromboplastic substance or thromboplastin.
1954 R. G. Macfarlane in H. W. Florey Lect. Gen. Pathol. x. 196 The classical theory, built up during the past fifty years, postulates a direct stimulator of prothrombin conversion which is usually called ‘thromboplastin’.
2003 Jrnl. Avian Med. & Surg. 17 73/1 Tissue thromboplastin, in conjunction with calcium and phospholipid, mediates the generation of thrombin from prothrombin.
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