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单词 ticlopidine
释义

ticlopidinen.

Brit. /tʌɪˈkləʊpᵻdiːn/, U.S. /ˌtaɪˈkloʊpədin/
Origin: Formed within English, by compounding. Etymons: thio- comb. form, chloro- comb. form2, pyridine n.
Etymology: < ti- (representing thio- comb. form) + clo- (representing chloro- comb. form2) + -pidine (representing pyridine n.), components of the molecular structure.
Pharmacology.
A drug that inhibits the aggregation of blood platelets (now largely superseded by clopidogrel).Chemical name: 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine, C14H14ClNS.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > anti-coagulants
anti-coagulant1905
heparin1918
Tromexan1949
warfarin1950
phenindione1955
ticlopidine1975
clopidogrel1989
1975 J. J. Thebault et al. in Clin. Pharmacol. & Therapeutics 18 485/1 Ticlopidine..has been shown to be a potent platelet aggregation inhibitor.
1989 Lancet 3 June 1215/1 This study provides evidence of a beneficial effect of ticlopidine in both men and women with a recent thromboembolic stroke.
2002 Jrnl. Kentucky Med. Assoc. 100 184 The thienopyridines, ticlopidine and clopidogrel, are useful alternatives for secondary stroke prevention in patients who do not respond to or cannot take aspirin.
This is a new entry (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1975
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