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单词 topoisomerase
释义

> as lemmas

topoisomerase
topoisomerase n.
Brit. /ˌtɒpəʊʌɪˈsɒməreɪz/
,
/ˌtɒpəʊʌɪˈsɒməreɪs/
,
U.S. /ˌtɑpoʊˌaɪˈsɑməˌreɪs/
,
/ˌtɑpoʊˌaɪˈsɑməˌreɪz/
Biochemistry any enzyme that alters the supercoiled form of a DNA molecule.
ΚΠ
1978 Devel. Biol. LXIV. 273/2 The enzyme has been referred to as ω-protein.., swivelase.., untwisting enzyme.., relaxing activity.., relaxing protein.., nicking-closing activity.., and DNA topoisomerase.
1979 Wang & Liu in J. H. Taylor Molecular Genetics III. ii. 66 We propose that they be called DNA topoisomerases.
1980 Sci. Amer. July 109/2 These nicking-closing enzymes, which are also called topoisomerases, generally require no energy source to function.
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