tranylcyprominen.
/trɑːnʌɪlˈsʌɪprəmiːn//tranʌɪlˈsʌɪprəmiːn/ Pharmacology.
A monoamine oxidase inhibitor, C9H11N, used in the treatment of severe depression (usually in the form of the sulphate).
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs
Marsilid1952
iproniazid1953
levallorphan1953
imipramine1958
Tofranil1958
isocarboxazid1959
Marplan1959
Nardil1959
nialamide1959
Niamid1959
phenelzine1959
tranylcypromine1959
Parnate1960
amitriptyline1961
monoamine oxidase inhibitor1962
nortriptyline1962
protriptyline1963
MAOI1965
maprotiline1970
mianserin1970
amoxapine1971
fluoxetine1975
paroxetine1977
Prozac1985
Seroxat1985
1959 Proc. Soc. Exper. Biol. & Med. 102 380 (heading) Some pharmacological observations on tranylcypromine (SKF trans-385).
1964 New Statesman 6 Mar. 354/1 An American anti-depressant drug—Parnate or tranylcypromine—has been declared unsafe by the US Food and Drug Administration.
1965 J. Pollitt Depression & its Treatm. iv. 56 The monoamine oxidase inhibitors include several members, among them phenelzine (Nardil), iproniazid (Marsilid),..and tranylcypromine (Parnate).
1976 Lancet 27 Nov. 1164/1 Six patients with neurogenic orthostatic hypotension were treated with a chemical preparation of tyramine and tranylcypromine.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1959