triamterenen.

/trʌɪˈamtəriːn/

Forms: Also triamterine.

Etymology: < triam- (in triamine n.) + -terene altered < pteridine n.

Pharmacology.

A yellow crystalline powder, C₁₂H₁₁N₇, used as a mild diuretic, usually as an adjunct to other diuretic drugs in cases where increased excretion of potassium is undesirable; 6-phenylpteridine-2,4,7-triamine.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific

Haarlem oil1885

Salyrgan1924

mersalyl1936

acetazolamide1954

chlorothiazide1957

thiazide1959

triamterene1962

ethacrynic acid1963

frusemide1963

1962 Ann. Internal Med. 56 241/1 Observations in rats and dogs..demonstrated that triamterene (SK&F No. 8542)..possessed antimineralo-corticoid activity.

1964 Brit. Med. Jrnl. 13 June 1557/1 Triamterine is a pteridine compound (2,4,7-triamino-6-phenylpteridine) and is chemically unrelated to any of the previously available diuretics.

1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xi. 10/1 Triamterene increases the renal excretion of Na⁺ and Cl⁻ in approximately equal amounts and has no effect on HCO₃⁻ excretion.

1985 Brit. Med. Jrnl. 9 Nov. 1337/1 Folate may be antagonised by..triamterene.

1987 M. J. Neal Med. Pharmacol. at Glance xiii. 33/2 Amiloride and triamterene decrease the luminal membrane Na⁺ permeability in the distal nephron.

This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020).

单词	triamterene
释义	triamterenen. /trʌɪˈamtəriːn/ Forms: Also triamterine. Etymology: < triam- (in triamine n.) + -terene altered < pteridine n. Pharmacology. A yellow crystalline powder, C₁₂H₁₁N₇, used as a mild diuretic, usually as an adjunct to other diuretic drugs in cases where increased excretion of potassium is undesirable; 6-phenylpteridine-2,4,7-triamine. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific Haarlem oil1885 Salyrgan1924 mersalyl1936 acetazolamide1954 chlorothiazide1957 thiazide1959 triamterene1962 ethacrynic acid1963 frusemide1963 1962 Ann. Internal Med. 56 241/1 Observations in rats and dogs..demonstrated that triamterene (SK&F No. 8542)..possessed antimineralo-corticoid activity. 1964 Brit. Med. Jrnl. 13 June 1557/1 Triamterine is a pteridine compound (2,4,7-triamino-6-phenylpteridine) and is chemically unrelated to any of the previously available diuretics. 1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xi. 10/1 Triamterene increases the renal excretion of Na⁺ and Cl⁻ in approximately equal amounts and has no effect on HCO₃⁻ excretion. 1985 Brit. Med. Jrnl. 9 Nov. 1337/1 Folate may be antagonised by..triamterene. 1987 M. J. Neal Med. Pharmacol. at Glance xiii. 33/2 Amiloride and triamterene decrease the luminal membrane Na⁺ permeability in the distal nephron. This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020). < n.1962
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