trihexyphenidyln.

Brit.

/ˌtrʌɪhɛksɪˈfɛnɪdʌɪl/,

/ˌtrʌɪhɛksɪˈfɛnɪdɪl/,

/ˌtrʌɪhɛksɪˈfiːnɪdʌɪl/,

/ˌtrʌɪhɛksɪˈfiːnɪdɪl/, U.S.

/ˌtraɪˌhɛksiˈfɛnɪdɪl/,

/ˌtraɪˌhɛksiˈfinɪdaɪl/

Origin: Formed within English, by derivation. Etymons: tri- comb. form, hexyl n., phen- comb. form, piperidine n., -yl suffix.

Etymology: < tri- comb. form + -hexy- (in hexyl n.) + phen- comb. form + -id- (in piperidine n.) + -yl suffix.

Pharmacology.

An antimuscarinic drug that has an antispasmodic action on smooth muscle and is used to treat parkinsonism and some other movement disorders; also called benzhexol.Chemical name: 1-cyclohexyl-1-phenyl-3-piperidinopropan-1-ol C₂₀H₃₁NO.A proprietary name for this drug is Artane n. This and other antimuscarinic drugs are sometimes abused for their psychoactive, esp. hallucinogenic, properties.

ΚΠ

1949 Jrnl. Amer. Med. Assoc. 140 1317/1 Trihexyphenidyl (artane..) is a member of a new series of antispasmodic compounds.

1967 Brit. Jrnl. Psychiatry 113 213/1 Benzhexol hydrochloride (Artane, Pipanol, Trihexyphenidyl) was the first of a range of synthetic antispasmodic drugs to be made available for the symptomatic treatment of Parkinsonism.

1990 N.Y. Times (Nexis) 14 June b12/1 A man with Parkinson's disease who had functioned well on Artane (trihexyphenidyl) until a severe depression.

2004 A. C. Abrams et al. Clin. Drug Therapy (ed. 8) xx. 325/1 Trihexyphenidyl relieves smooth muscle spasm by a direct action on the muscle and by inhibiting the parasympathetic nervous system.

This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022).

单词	trihexyphenidyl
释义	trihexyphenidyln. Brit. /ˌtrʌɪhɛksɪˈfɛnɪdʌɪl/, /ˌtrʌɪhɛksɪˈfɛnɪdɪl/, /ˌtrʌɪhɛksɪˈfiːnɪdʌɪl/, /ˌtrʌɪhɛksɪˈfiːnɪdɪl/, U.S. /ˌtraɪˌhɛksiˈfɛnɪdɪl/, /ˌtraɪˌhɛksiˈfinɪdaɪl/ Origin: Formed within English, by derivation. Etymons: tri- comb. form, hexyl n., phen- comb. form, piperidine n., -yl suffix. Etymology: < tri- comb. form + -hexy- (in hexyl n.) + phen- comb. form + -id- (in piperidine n.) + -yl suffix. Pharmacology. An antimuscarinic drug that has an antispasmodic action on smooth muscle and is used to treat parkinsonism and some other movement disorders; also called benzhexol.Chemical name: 1-cyclohexyl-1-phenyl-3-piperidinopropan-1-ol C₂₀H₃₁NO.A proprietary name for this drug is Artane n. This and other antimuscarinic drugs are sometimes abused for their psychoactive, esp. hallucinogenic, properties. ΚΠ 1949 Jrnl. Amer. Med. Assoc. 140 1317/1 Trihexyphenidyl (artane..) is a member of a new series of antispasmodic compounds. 1967 Brit. Jrnl. Psychiatry 113 213/1 Benzhexol hydrochloride (Artane, Pipanol, Trihexyphenidyl) was the first of a range of synthetic antispasmodic drugs to be made available for the symptomatic treatment of Parkinsonism. 1990 N.Y. Times (Nexis) 14 June b12/1 A man with Parkinson's disease who had functioned well on Artane (trihexyphenidyl) until a severe depression. 2004 A. C. Abrams et al. Clin. Drug Therapy (ed. 8) xx. 325/1 Trihexyphenidyl relieves smooth muscle spasm by a direct action on the muscle and by inhibiting the parasympathetic nervous system. This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022). < n.1949
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