trypsinn.
/ˈtrɪpsɪn/, U.S. /ˈtrɪpsᵻn/ Physiology and Chemistry.
The chief digestive ferment of the pancreatic juice, which converts proteins into peptones.
ΚΠ
1877 M. Foster Text Bk. Physiol. ii. i. 175 A proteid is digested by trypsin, such being the name which Kühne gives to the purified pancreatic ferment.
1907 Westm. Gaz. 12 Dec. 12/2 The new treatment of cancer by the pancreatic ferments, trypsin and amylopsin..suggested by Dr. Beard.
Compounds
ΚΠ
1903 Jrnl. Chem. Soc. 84 ii. 559 Liberation of Trypsin from Trypsin-zymogen.
1908 Practitioner Aug. 351 The trypsin-sodium carbonate of the pancreatic juice.
Derivatives
trypˈsinogen n. /-dʒən/ [-gen comb. form 1] a granular substance occurring in the pancreas, from which trypsin is formed.
ΚΠ
1890 J. S. Billings National Med. Dict. II Trypsinogen.
1900 Lancet 27 Oct. 1187/1 The fact observed by Heidenhain of the continuous formation and storing up trypsinogen in the pancreas, and its subsequent transformation into trypsin during the culmen of gastric digestion, proved that the former substance..enjoyed an origin quite independent of all influence outside the pancreas.
1907 H. W. Bettmann in Med. Record 3 Aug. 171 The intestinal juice contains two other ferments.., enterokinase, and erepsin. The former activates the pancreatic juice by transforming trypsinogen into trypsin.
ˈtrypsogen n. [abbreviation of trypsinogen n.] (a) = trypsinogen n.; (b) a drug prepared from trypsin and other ferments with gold and arsenic bromides, used in diabetes, etc. (Dorland).
ΚΠ
1883 Science 1 372/1 The absence of oxygen from the blood has led to a reconversion of trypsin into trypsogen.
This entry has not yet been fully updated (first published 1915; most recently modified version published online March 2022).
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