tuberculinn.

Brit.

/t(j)ᵿˈbəːkjᵿlɪn/,

/tʃᵿˈbəːkjᵿlɪn/, U.S.

/təˈbərkjəlᵻn/,

/ˌt(j)uˈbərkjəlᵻn/

Forms: 1800s– tuberculin, 1800s– tuberculine.

Origin: Formed within English, by derivation. Etymons: tuberculosis n., -in suffix¹.

Etymology: < tubercul- (in tuberculosis n.) + -in suffix¹.In sense 2 after German Tuberculin (1891 or earlier; now Tuberkulin ). With the form tuberculine compare -ine suffix⁴.

Medicine.

†1. A toxic substance (supposedly) present in the tubercles or bacilli of tuberculosis. Obsolete. rare.

ΚΠ

1861 L. M. Lawson Pract. Treat. Phthisis Pulmonalis i. xiii. 160 Whether these peculiar substances are to be regarded in the light of a special tubercular element, (tuberculin?) it would be fruitless in the present state of our knowledge to inquire.

1891 Brit. Med. Jrnl. 7 Feb. 285/2 Professor Crookshank concluded that the tubercle bacillus probably produced a complex proteid poison, in which, as in anthrax (Martin), the alkaloid of tubercle or tuberculine was in a nascent condition.

2. Originally (now more fully old tuberculin): a liquid prepared by heat-sterilizing, filtering, and concentrating broth cultures of the tubercle bacillus ( Mycobacterium tuberculosis), used first in the treatment and later in the diagnosis of tuberculosis. In later use also: any of various other preparations containing proteins of M. tuberculosis or other mycobacteria.Tuberculin was introduced by Robert Koch (1890) as an agent for the treatment of tuberculosis, and in its original form is also known as Koch's tuberculin, Koch's old tuberculin, and (formerly) Koch's lymph and Koch's fluid (see Koch n.).

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used as testing agents

tuberculin1891

lepromin1929

penatin1942

sulphobromophthalein1945

toxoplasmin1948

Metopirone1960

metyrapone1962

leprolin1971

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tuberculosis

Koch's tuberculin1890

tuberculin1891

tuberculocidin1891

tuberculocide1892

Sanocrysin1924

promizole1944

streptomycin1944

para-aminosalicylic acid1946

pyrazinamide1947

viomycin1950

Marsilid1952

thiacetazone1952

iproniazid1953

isoniazid1953

isonicotinic hydrazide1956

ethionamide1959

strep1959

rifampicin1966

rifampin1968

1891 Daily News 12 Feb. 6/5 Dr. Koch's lymph has received the name of ‘tuberculine’.

1891 Brit. Med. Jrnl. 14 Feb. 374/2 The new supply of Koch's lymph is sent out in bottles labelled ‘Tuberculin, Dr. Libbertz,’ so that, after having had all sorts of names..the lymph may now be considered officially christened.

1896 Westm. Gaz. 10 Mar. 4/1 At the Balneological Congress,..Dr. Kaatzer spoke very highly of the value of tuberculin in phthisis... Professor Liebreich asserted that the cure of lupus by tuberculin was more apparent than real.

1930 Tubercle July 434 To exclude previous infection, all animals were skin-tested with old tuberculin prior to inoculation.

1982 Jrnl. Biol. Standardization 10 286 The substantial difference between the reactions to bovine and avian tuberculins shows that the former also has a high degree of specificity.

2012 Times Higher Ed. Suppl. (Nexis) 25 Oct. 32 Should we kill badgers to prevent culling those cattle that react to tuberculin because they have come into contact with TB bacteria?

Compounds

C1. General attributive.

ΚΠ

1891 Brit. Med. Jrnl. 28 Feb. 485/1 He [sc. Professor Fraenkel] carefully weighed the pros. and cons. of the tuberculin treatment.

1896 Lancet 22 Feb. 477/2 Straus and Tessier..found that strong reactions occurred in cases of secondary syphilis when tuberculin injections were made.

1901 Jrnl. Compar. Pathol. & Therapeutics 14 372 With my tuberculin syringe I slowly inject 8 cc. of pure antitetanin.

1967 Times 30 Nov. 11/4 We ensure that the doses of bacillus will be small by culling all tuberculin reactors from our milking herds.

1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) vi. 103 Isoniazid may be used alone for chemoprophylaxis of exposed or recently infected individuals (‘tuberculin converters’).

1997 L. Yablonsky Story of Junk 250 Poking through the crowded shelves, we look for laxatives and lubricants, condoms, and tuberculin spikes.

2008 D. R. Flower Bioinformatics Vaccinol. i. 43 Calmette studied Koch's tuberculin treatment for tuberculosis and soon found it to be ineffective against TB.

C2.

tuberculin reaction n. reaction to the administration of tuberculin, esp. as a diagnostic test; an instance of this; spec. a positive reaction in this test (typically consisting of a circumscribed area of thickening and reddening of the skin).

ΚΠ

1891 Amer. Practitioner & News 9 May 311/2 Great reduction of strength is likewise an unfavorable condition for its action, since the tuberculin reaction, if at all marked, runs down the patient still further.

1906 Rev. of Reviews Sept. 366 [It] showed no tuberculine reaction.

1955 Sci. News Let. 1 Oct. 221/1 The tuberculin test is a skin test. A tuberculin reaction means that tuberculosis germs have invaded the person's body and sensitized it to proteins of the TB germ.

2001 M. D. Mezey et al. Encycl. Elder Care 650/2 The larger the tuberculin reaction, the more likely it is due to exposure to Mycobacterium tuberculosis rather than BCG or a non-tuberculous infection.

tuberculin test n. the administration of tuberculin, usually by intradermal injection, as a test for infection (past or present) with tubercle bacilli or other mycobacteria.

ΘΚΠ

the world > health and disease > healing > diagnosis or prognosis > tests > [noun] > specific test

pneobiomantia1846

blood test1851

drug test1863

Romberg test1872

Rinne1881

Romberg's sign1884

tuberculin test1892

guaiac test1894

agglutination1896

percolation test1899

Pirquet test1908

skin test1908

Wassermann1909

Romberg1915

Pandy('s) test1916

glucose tolerance test1917

Kolmer1921

patch test1922

skin testing1923

provocation1924

Kolmer–Wassermann1925

Queckenstedt1928

Kline1929

Prausnitz–Küstner1929

cross-match1930

Mantoux test1931

paraffin test1935

Paul–Bunnell test1935

stress test1937

Burpee test1939

lepromin test1939

patch testing1941

pinprick1941

breath test1945

provocation test1948

protamine titration1949

Coombs test1950

smear test1950

Schilling test1955

tanned-(red-)cell1956

amniocentesis1958

Pap smear1963

Pap test1963

drugs test1967

Schultz–Charlton1974

amnio1984

cross-matching-

the world > health and disease > healing > diagnosis or prognosis > tests > test [verb (transitive)] > specific test

tuberculin test1892

cross-match1930

skin-test1930

patch-test1940

1892 Brit. Med. Jrnl. 9 Apr. 781/1 Until the whole 30 animals of Mr. Gillingham's herd that reacted have been killed the value of the tuberculin test in this case cannot be judged.

1908 Med. Ann. 662 Tuberculin Test.—This test, prepared by the Pasteur Institute of Lille, claims to be diagnostic of tuberculosis in man.

1950 J. G. Davis Dict. Dairying 721 Three forms of tuberculin test have been evolved—the ophthalmic, the subcutaneous and the intradermal.

1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) xxvii. 392 The preferred intracutaneous tuberculin test (Mantoux test) with various tuberculins (protein derivatives of bacilli) is becoming increasingly useful in the diagnosis of the mycobacterioses.

2009 Mirror (Ulster ed.) (Nexis) 21 Aug. 15 A farmer is to go on trial after being charged with failing to present his herd of cattle for a tuberculin test.

tuberculin test v. transitive to perform a tuberculin test upon.

ΚΠ

1894 Bull. Vermont Agric. Exper. Station No. 42 62 No new animal should be admitted from herds in which contagious disease has existed..unless tuberculin-tested.

1937 Amer. Rev. Tuberculosis 35 598 A classification of the 56,688 persons tuberculin-tested according to age disclosed the fact that boys and girls between ten and nineteen years of age comprised almost two-thirds of the groups reported.

2005 Daily Tel. 8 Dec. 21/3 I have been a veterinary surgeon for more than 50 years and first tuberculin-tested cattle when the TB eradication scheme restarted after the Second World War.

tuberculin-tested adj. (a) (of an animal or person) that has undergone a tuberculin test; (b) (esp. of milk) produced by tuberculin-tested cows.

ΘΚΠ

the world > health and disease > healing > diagnosis or prognosis > tests > [adjective] > specific tests

drug testing1841

Head1893

Widal1896

tuberculin-tested1898

Schick1916

Kahn1922

T.T.1927

P–K1938

Papanicolaou1947

drugs testing1965

lymphocytotoxicity1965

patch-tested1990

1898 Proc. Amer. Chem. Soc. 20 49 The milk is obtained from healthy tuberculin-tested cattle.

1898 Milwaukee (Wisconsin) Sentinel 21 Sept. 3/4 The tuberculin tested milk and cream (guaranteed to be free from any taint of tuberculosis or other disease or impurity) is supplied from these herds.

1936 Milk (Special Designation Order) xi. §1 A licence to sell milk as ‘Certified’ or as ‘Grade A (Tuberculin Tested)’ shall be deemed to be a licence authorising the use of the special designation ‘Tuberculin Tested’.

2003 Gloucestershire Echo (Nexis) 21 Apr. 10 He replaced the herd with tuberculin tested cattle from a clean area in which the disease had been 100 per cent eradicated.

Derivatives

tuˈberculinize v. (also tuberculinise) transitive (a) to treat or test with tuberculin; (b) = tuberculize v. 2.

ΘΚΠ

the world > health and disease > healing > medical treatment > treatment by medicine or drug > treat with drugs [verb (transitive)] > treat with specific drugs or medicines

tartar1647

blue-pill1824

mercurialize1825

opium1825

treacle1839

tartar-emeticize1844

quinine1858

quininize1860

cinchonize1863

veratrize1891

oxalate1894

tuberculinize1897

citrate1903

strychninize1934

juice1973

1897 Clin. Jrnl. 13 Oct. 398/1 Passive immunisation with the serum of animals immunised with tuberculin (tuberculinised).

1898 Philadelphia Med. Jrnl. 2 198/2 In equal volume, the serum from a horse that has been subjected to these injections will act a little more quickly than the serum from animals that have been tuberculized or tuberculinized.

1957 Brit. Med. Jrnl. 7 Sept. 591/1 Cow's milk is an important medium through which immunity against tuberculosis is acquired, and it is gratifying to know that most people are ‘tuberculinized’ before adult life.

2010 BMC Vet. Res. (Electronic ed.) Apr. We also want to thank the University of Zambia drivers who had to endure excessively long waiting hours while we conducted interviews and tuberculinised cattle.

tuˈberculinized adj. (also tuberculinised) (a) affected by or containing tuberculin (rare); tested or treated with tuberculin; (b) = tuberculized adj.

ΚΠ

1892 New Eng. Med. Gaz. 27 69 And Koch's ‘tuberculin’, injected in cases of lupus, stops the action of the bacillus tuberc., not so much by producing ‘necrotic tissue’ as tuberculinized tissue.

1895 A. H. Buck Ref. Handbk. Med. Sci. IX. 900/2 Comparing..the condition of the various organs of the tuberculinized with that of the same in healthy animals.

1938 Tubercle 19 566/1 Thoroughly tuberculinized animals subsequently infected with virulent tubercle bacilli and kept tuberculinized by means of daily injections of 1 c.c. of undiluted tuberculin do not develop allergy at any time.

tuˌberculiniˈzation n. (also tuberculinisation) (a) treatment or testing with tuberculin; (b) = tuberculization n.

ΘΚΠ

the world > health and disease > healing > medical treatment > treatment by medicine or drug > [noun] > treatment with specific substances

mercurialization1825

cinchonization1875

helleborism1883

cocainization1887

tuberculinization1892

gold therapy1894

strychninization1898

venomization1905

strychnization1916

heparinization1956

reserpinization1959

1891 N. Amer. Jrnl. Homeopathy 39 633 Auto-tuberculinization in lupus.—Unna, of Hamburg, has devised a method, based upon very ingenious reasoning, of treating lupus by its own tuberculin.]

1892 Brit. Jrnl. Dermatol. 4 196 This process of local tuberculinization offers, in Unna's opinion, the real explanation of the good effects derived from Squire and Vidal's scarification treatment.

1938 Brit. Med. Jrnl. 7 May 992/1 The value of the Mantoux test as a clinical aid seems to be doubted in some quarters, apparently on the assumption that there is almost complete tuberculinization of the population.

2009 Vaccine 27 2313/2 Subsequently, the animals were stratified by age, breed, initial tuberculinisation reaction and in vitro lymphoproliferative reaction to bovine tuberculin.

This entry has been updated (OED Third Edition, June 2014; most recently modified version published online March 2022).

单词	tuberculin
释义	tuberculinn. Brit. /t(j)ᵿˈbəːkjᵿlɪn/, /tʃᵿˈbəːkjᵿlɪn/, U.S. /təˈbərkjəlᵻn/, /ˌt(j)uˈbərkjəlᵻn/ Forms: 1800s– tuberculin, 1800s– tuberculine. Origin: Formed within English, by derivation. Etymons: tuberculosis n., -in suffix¹. Etymology: < tubercul- (in tuberculosis n.) + -in suffix¹.In sense 2 after German Tuberculin (1891 or earlier; now Tuberkulin ). With the form tuberculine compare -ine suffix⁴. Medicine. †1. A toxic substance (supposedly) present in the tubercles or bacilli of tuberculosis. Obsolete. rare. ΚΠ 1861 L. M. Lawson Pract. Treat. Phthisis Pulmonalis i. xiii. 160 Whether these peculiar substances are to be regarded in the light of a special tubercular element, (tuberculin?) it would be fruitless in the present state of our knowledge to inquire. 1891 Brit. Med. Jrnl. 7 Feb. 285/2 Professor Crookshank concluded that the tubercle bacillus probably produced a complex proteid poison, in which, as in anthrax (Martin), the alkaloid of tubercle or tuberculine was in a nascent condition. 2. Originally (now more fully old tuberculin): a liquid prepared by heat-sterilizing, filtering, and concentrating broth cultures of the tubercle bacillus ( Mycobacterium tuberculosis), used first in the treatment and later in the diagnosis of tuberculosis. In later use also: any of various other preparations containing proteins of M. tuberculosis or other mycobacteria.Tuberculin was introduced by Robert Koch (1890) as an agent for the treatment of tuberculosis, and in its original form is also known as Koch's tuberculin, Koch's old tuberculin, and (formerly) Koch's lymph and Koch's fluid (see Koch n.). ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used as testing agents tuberculin1891 lepromin1929 penatin1942 sulphobromophthalein1945 toxoplasmin1948 Metopirone1960 metyrapone1962 leprolin1971 the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tuberculosis Koch's tuberculin1890 tuberculin1891 tuberculocidin1891 tuberculocide1892 Sanocrysin1924 promizole1944 streptomycin1944 para-aminosalicylic acid1946 pyrazinamide1947 viomycin1950 Marsilid1952 thiacetazone1952 iproniazid1953 isoniazid1953 isonicotinic hydrazide1956 ethionamide1959 strep1959 rifampicin1966 rifampin1968 1891 Daily News 12 Feb. 6/5 Dr. Koch's lymph has received the name of ‘tuberculine’. 1891 Brit. Med. Jrnl. 14 Feb. 374/2 The new supply of Koch's lymph is sent out in bottles labelled ‘Tuberculin, Dr. Libbertz,’ so that, after having had all sorts of names..the lymph may now be considered officially christened. 1896 Westm. Gaz. 10 Mar. 4/1 At the Balneological Congress,..Dr. Kaatzer spoke very highly of the value of tuberculin in phthisis... Professor Liebreich asserted that the cure of lupus by tuberculin was more apparent than real. 1930 Tubercle July 434 To exclude previous infection, all animals were skin-tested with old tuberculin prior to inoculation. 1982 Jrnl. Biol. Standardization 10 286 The substantial difference between the reactions to bovine and avian tuberculins shows that the former also has a high degree of specificity. 2012 Times Higher Ed. Suppl. (Nexis) 25 Oct. 32 Should we kill badgers to prevent culling those cattle that react to tuberculin because they have come into contact with TB bacteria? Compounds C1. General attributive. ΚΠ 1891 Brit. Med. Jrnl. 28 Feb. 485/1 He [sc. Professor Fraenkel] carefully weighed the pros. and cons. of the tuberculin treatment. 1896 Lancet 22 Feb. 477/2 Straus and Tessier..found that strong reactions occurred in cases of secondary syphilis when tuberculin injections were made. 1901 Jrnl. Compar. Pathol. & Therapeutics 14 372 With my tuberculin syringe I slowly inject 8 cc. of pure antitetanin. 1967 Times 30 Nov. 11/4 We ensure that the doses of bacillus will be small by culling all tuberculin reactors from our milking herds. 1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) vi. 103 Isoniazid may be used alone for chemoprophylaxis of exposed or recently infected individuals (‘tuberculin converters’). 1997 L. Yablonsky Story of Junk 250 Poking through the crowded shelves, we look for laxatives and lubricants, condoms, and tuberculin spikes. 2008 D. R. Flower Bioinformatics Vaccinol. i. 43 Calmette studied Koch's tuberculin treatment for tuberculosis and soon found it to be ineffective against TB. C2. tuberculin reaction n. reaction to the administration of tuberculin, esp. as a diagnostic test; an instance of this; spec. a positive reaction in this test (typically consisting of a circumscribed area of thickening and reddening of the skin). ΚΠ 1891 Amer. Practitioner & News 9 May 311/2 Great reduction of strength is likewise an unfavorable condition for its action, since the tuberculin reaction, if at all marked, runs down the patient still further. 1906 Rev. of Reviews Sept. 366 [It] showed no tuberculine reaction. 1955 Sci. News Let. 1 Oct. 221/1 The tuberculin test is a skin test. A tuberculin reaction means that tuberculosis germs have invaded the person's body and sensitized it to proteins of the TB germ. 2001 M. D. Mezey et al. Encycl. Elder Care 650/2 The larger the tuberculin reaction, the more likely it is due to exposure to Mycobacterium tuberculosis rather than BCG or a non-tuberculous infection. tuberculin test n. the administration of tuberculin, usually by intradermal injection, as a test for infection (past or present) with tubercle bacilli or other mycobacteria. ΘΚΠ the world > health and disease > healing > diagnosis or prognosis > tests > [noun] > specific test pneobiomantia1846 blood test1851 drug test1863 Romberg test1872 Rinne1881 Romberg's sign1884 tuberculin test1892 guaiac test1894 agglutination1896 percolation test1899 Pirquet test1908 skin test1908 Wassermann1909 Romberg1915 Pandy('s) test1916 glucose tolerance test1917 Kolmer1921 patch test1922 skin testing1923 provocation1924 Kolmer–Wassermann1925 Queckenstedt1928 Kline1929 Prausnitz–Küstner1929 cross-match1930 Mantoux test1931 paraffin test1935 Paul–Bunnell test1935 stress test1937 Burpee test1939 lepromin test1939 patch testing1941 pinprick1941 breath test1945 provocation test1948 protamine titration1949 Coombs test1950 smear test1950 Schilling test1955 tanned-(red-)cell1956 amniocentesis1958 Pap smear1963 Pap test1963 drugs test1967 Schultz–Charlton1974 amnio1984 cross-matching- the world > health and disease > healing > diagnosis or prognosis > tests > test [verb (transitive)] > specific test tuberculin test1892 cross-match1930 skin-test1930 patch-test1940 1892 Brit. Med. Jrnl. 9 Apr. 781/1 Until the whole 30 animals of Mr. Gillingham's herd that reacted have been killed the value of the tuberculin test in this case cannot be judged. 1908 Med. Ann. 662 Tuberculin Test.—This test, prepared by the Pasteur Institute of Lille, claims to be diagnostic of tuberculosis in man. 1950 J. G. Davis Dict. Dairying 721 Three forms of tuberculin test have been evolved—the ophthalmic, the subcutaneous and the intradermal. 1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) xxvii. 392 The preferred intracutaneous tuberculin test (Mantoux test) with various tuberculins (protein derivatives of bacilli) is becoming increasingly useful in the diagnosis of the mycobacterioses. 2009 Mirror (Ulster ed.) (Nexis) 21 Aug. 15 A farmer is to go on trial after being charged with failing to present his herd of cattle for a tuberculin test. tuberculin test v. transitive to perform a tuberculin test upon. ΚΠ 1894 Bull. Vermont Agric. Exper. Station No. 42 62 No new animal should be admitted from herds in which contagious disease has existed..unless tuberculin-tested. 1937 Amer. Rev. Tuberculosis 35 598 A classification of the 56,688 persons tuberculin-tested according to age disclosed the fact that boys and girls between ten and nineteen years of age comprised almost two-thirds of the groups reported. 2005 Daily Tel. 8 Dec. 21/3 I have been a veterinary surgeon for more than 50 years and first tuberculin-tested cattle when the TB eradication scheme restarted after the Second World War. tuberculin-tested adj. (a) (of an animal or person) that has undergone a tuberculin test; (b) (esp. of milk) produced by tuberculin-tested cows. ΘΚΠ the world > health and disease > healing > diagnosis or prognosis > tests > [adjective] > specific tests drug testing1841 Head1893 Widal1896 tuberculin-tested1898 Schick1916 Kahn1922 T.T.1927 P–K1938 Papanicolaou1947 drugs testing1965 lymphocytotoxicity1965 patch-tested1990 1898 Proc. Amer. Chem. Soc. 20 49 The milk is obtained from healthy tuberculin-tested cattle. 1898 Milwaukee (Wisconsin) Sentinel 21 Sept. 3/4 The tuberculin tested milk and cream (guaranteed to be free from any taint of tuberculosis or other disease or impurity) is supplied from these herds. 1936 Milk (Special Designation Order) xi. §1 A licence to sell milk as ‘Certified’ or as ‘Grade A (Tuberculin Tested)’ shall be deemed to be a licence authorising the use of the special designation ‘Tuberculin Tested’. 2003 Gloucestershire Echo (Nexis) 21 Apr. 10 He replaced the herd with tuberculin tested cattle from a clean area in which the disease had been 100 per cent eradicated. Derivatives tuˈberculinize v. (also tuberculinise) transitive (a) to treat or test with tuberculin; (b) = tuberculize v. 2. ΘΚΠ the world > health and disease > healing > medical treatment > treatment by medicine or drug > treat with drugs [verb (transitive)] > treat with specific drugs or medicines tartar1647 blue-pill1824 mercurialize1825 opium1825 treacle1839 tartar-emeticize1844 quinine1858 quininize1860 cinchonize1863 veratrize1891 oxalate1894 tuberculinize1897 citrate1903 strychninize1934 juice1973 1897 Clin. Jrnl. 13 Oct. 398/1 Passive immunisation with the serum of animals immunised with tuberculin (tuberculinised). 1898 Philadelphia Med. Jrnl. 2 198/2 In equal volume, the serum from a horse that has been subjected to these injections will act a little more quickly than the serum from animals that have been tuberculized or tuberculinized. 1957 Brit. Med. Jrnl. 7 Sept. 591/1 Cow's milk is an important medium through which immunity against tuberculosis is acquired, and it is gratifying to know that most people are ‘tuberculinized’ before adult life. 2010 BMC Vet. Res. (Electronic ed.) Apr. We also want to thank the University of Zambia drivers who had to endure excessively long waiting hours while we conducted interviews and tuberculinised cattle. tuˈberculinized adj. (also tuberculinised) (a) affected by or containing tuberculin (rare); tested or treated with tuberculin; (b) = tuberculized adj. ΚΠ 1892 New Eng. Med. Gaz. 27 69 And Koch's ‘tuberculin’, injected in cases of lupus, stops the action of the bacillus tuberc., not so much by producing ‘necrotic tissue’ as tuberculinized tissue. 1895 A. H. Buck Ref. Handbk. Med. Sci. IX. 900/2 Comparing..the condition of the various organs of the tuberculinized with that of the same in healthy animals. 1938 Tubercle 19 566/1 Thoroughly tuberculinized animals subsequently infected with virulent tubercle bacilli and kept tuberculinized by means of daily injections of 1 c.c. of undiluted tuberculin do not develop allergy at any time. tuˌberculiniˈzation n. (also tuberculinisation) (a) treatment or testing with tuberculin; (b) = tuberculization n. ΘΚΠ the world > health and disease > healing > medical treatment > treatment by medicine or drug > [noun] > treatment with specific substances mercurialization1825 cinchonization1875 helleborism1883 cocainization1887 tuberculinization1892 gold therapy1894 strychninization1898 venomization1905 strychnization1916 heparinization1956 reserpinization1959 1891 N. Amer. Jrnl. Homeopathy 39 633 Auto-tuberculinization in lupus.—Unna, of Hamburg, has devised a method, based upon very ingenious reasoning, of treating lupus by its own tuberculin.] 1892 Brit. Jrnl. Dermatol. 4 196 This process of local tuberculinization offers, in Unna's opinion, the real explanation of the good effects derived from Squire and Vidal's scarification treatment. 1938 Brit. Med. Jrnl. 7 May 992/1 The value of the Mantoux test as a clinical aid seems to be doubted in some quarters, apparently on the assumption that there is almost complete tuberculinization of the population. 2009 Vaccine 27 2313/2 Subsequently, the animals were stratified by age, breed, initial tuberculinisation reaction and in vitro lymphoproliferative reaction to bovine tuberculin. This entry has been updated (OED Third Edition, June 2014; most recently modified version published online March 2022). < n.1861
随便看	subbotniki subbotniks subbottom subbourdon subbrachial subbrachian subbrachiate subbrachycephalic subbrachycephalous subbrachycephaly subbranch subbranched subbranches subbred subbreed subbreeding subbreeds subbrigade subbrigadier subbromide subbureau subbuteo subbuteo team subbuteo tournament subcabinet