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单词 urokinase
释义

urokinasen.

/jʊərəʊˈkʌɪneɪz/
Etymology: < uro- comb. form1 + kinase n.
Biochemistry and Pharmacology.
An enzyme which catalyses the conversion of plasminogen to plasmin and is used in the treatment of blood clots.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > biological product > [noun] > specific
lardc1420
sevumc1440
larding1582
protamine1874
renin1894
serum1895
sturine1896
iodothyrin1897
zymin1901
heparin1918
antireticular cytotoxic serum1942
urokinase1952
cryoprecipitate1956
xenoantiserum1973
anti-serum-
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > thrombolytics
urokinase1952
thrombolytic1965
ancrod1970
1952 G. W. Sobel et al. in Amer. Jrnl. Physiol. CLXXI. 768/2 Normal human and dog urine contains..a potent activator of profibrinolysin (plasminogen). The activator..we have designated urokinase.
1977 Daily Colonist (Victoria, Brit. Columbia) 23 Oct. 10/5 Urokinase is used in the treatment of blood clots and scientists said it has the potential of preventing 50,000 deaths per year in the United States alone.
1983 J. A. Davies & G. McNicol in D. J. Weatherall et al. Oxf. Textbk. Med. II. xix. 132/2 Urokinase is produced naturally by cells in the kidney and is present in human urine, probably to aid maintenance of ureteric patency.
This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2021).
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n.1952
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