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单词 zenker's degeneration
释义

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Zenker's degeneration
1. In the genitive, attributive, and with of, esp. in Zenker's degeneration. Designating a type of degeneration affecting skeletal and cardiac muscle, in which fibres lose their striations and appear uniformly eosinophilic.Such degeneration was originally described in cases of typhoid fever, but also occurs in other infectious diseases and as a result of nutritional deficiency, toxin ingestion, etc.
ΚΠ
1872 Trans. Clin. Soc. 1871–2 5 214 Here and there some of the fibres presented the advanced condition of the waxy degeneration of Zenker.
1898 W. S. Lazarus-Barlow Man. Gen. Pathol. xii. 521 In Zenker's degeneration the muscular fibres themselves look dull and semi-opaque, and microscopically are found to have lost their striation.
1900 Jrnl. Compar. Pathol. & Vet. Arch. 21 751 The degeneration of the psoas muscle is quite analogous to the Zenker degeneration seen in typhoid fever.
1966 G. P. Wright et al. Systemic Pathol. I. xvi. 525/1 Other findings in typhoid include..Zenker's degeneration of the abdominal muscles.
2016 Mitochondrion 30 36/2 Cases were further confirmed to suffer from AM [= atypical myopathy] on the basis of..histopathological findings showing a multifocal process compatible with Zenker's degeneration and necrosis in fibres of postural and/or respiratory muscles.
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