the world > space > relative position > central condition or position > [preposition] > in the middle or midst (of) (5)
With reference to physical location: in the centre, exactly or approximately, of. Obsolete or merged in sense A. 2.
In the centre of; = amid, prep. 1a. Obsolete or merged in sense B. 2.
Amid, amidst; in the middle (of).
Without article: in midst (of). Now rare (chiefly poetic in later use).