In such a way as to be oppressive, painful, or hurtful to the affairs, person, or feelings of any one; to an oppressive or injurious extent…

sorrowfully, sadly, lamentably, grievously; harmfully, injuriously; angrily, wrathfully.

Grievously, excessively.

With prepositions. on, upon the back of: weighing upon as a burden or incubus; falling upon as an assailant. Also colloquial, harassing, annoying. So…

in a pestering way.