A persecutor. Obsolete.

(a) a suppurating, oozing, or non-healing sore (now rare); (b) (figurative) a persistent problem; a constant nuisance or irritation.

figurative (originally Scottish). A person who or thing which is destructive, noxious, or troublesome; the bane of something. In later use also: an…

A person or thing that harasses or distresses.

One who or that which grates; chiefly figurative said of a person (or thing) that performs some harassing, exhausting, or ‘wearing’ process. Obsolete.

A person who harasses another or others.

A person who causes affliction or distress; an oppressor, a tormentor.

One who inflicts, in senses of the verb. (Usually const. of the thing inflicted.)

figurative (or in figurative context): Anything that causes pain, grief, or trouble; in various metaphors, similes, and proverbial expressions, as a…

A person or thing that weighs upon and oppresses like a nightmare.

Occupation with business to an inconvenient or burdensome degree; pressure of business; (with plural) affairs that occupy and trouble one. Obsolete…

one who or that which harasses.

Scottish dialect. Of persons: a nuisance, a pest, a good-for-nothing.

Extended and allusive uses. Something that continues to punish, persecute, or annoy a person relentlessly. Obsolete.

Chiefly regional. As a count noun: a person who or thing which is troublesome or annoying; a nuisance; a pest. Now rare.

A person who or thing which pesters; a nuisance.

One who baits or worries; figurative a tormenter, a ‘tease’.

figurative. That which plagues or troubles; disaster, calamity; an instance of this; a cause of trouble, a plague. Later, in weakened sense: a…

Esp. in Jewish usage: a pestering, nagging, or irritating person; a bore. Cf. noodge, n.