Prone to hypochondria, or the hyp (hyp, n.); in low spirits; given to unwarranted anxiety, esp. regarding one's health. Also: of, relating to, or…

Of a person, mental state, etc.: characterized by excessive gloom or apprehension, or (in later use) by an unhealthy preoccupation with disease…

Affected by or prone to hypochondria; low-spirited or anxious, esp. about one's health; = hippish, adj.

figurative. Showing depression of spirits like that of a person suffering from dyspepsia; morbidly despondent or gloomy.