Of something other than food or drink: liable to cause nausea or vomiting; repellent, extremely disagreeable.

Despicable; highly unpleasant; extremely annoying. Also occasionally as n.: an annoying or unpleasant person (chiefly as a form of address).

Nasty, highly unpleasant; extremely annoying.

Terrifying, extremely unpleasant or distressing; that causes nausea or severely upsets the stomach.

Causing (or liable to cause) the toes to curl as an emotional response, esp. in acute embarrassment or disgust; uncomfortably embarrassing or…

Extremely unpleasant or difficult; awful, dreadful, hellish.

Of a person (esp. a woman): ugly, very unattractive. Of a thing: extremely unappealing or unpleasant, horrible.