transitive. To treat without due reverence; to profane, defile; spec. to desecrate or destroy (a sacred place).

transitive. In extended use. To misuse, abuse, or defile (a person or thing) to which respect or reverence is due.

transitive. To violate or break (a promise, bond, etc.); to profane.

transitive. To take away its consecrated or sacred character from (anything); to treat as not sacred or hallowed; to profane.