transitive. To irritate or inflame (a wound, etc.). Also figurative and in figurative contexts. Cf. angry, adj. 10a. Now rare (archaic and regional…

transitive. To cause (flesh, wounds, etc.) to fester; to make painful. Also with up. Also in figurative contexts. Obsolete.

To irritate physically; to render sore, chafe.

transitive. = proritate, v.

transitive. To cause irritation, damage, or harm to (a part of the body). Obsolete.

transitive. Of things: To act upon or affect so as to irritate; esp. to pluck, nip, pinch, or tear (a part of the body) by means of small or sharp…

transitive. To provoke, incite; to irritate.

Pathology. To excite (a bodily organ or part) to morbid action, or to abnormal condition; to bring into a morbidly excited condition, or produce an…

transitive. To irritate (physically); to inflame.